Search for dissertations about: "S100A9"

Showing result 1 - 5 of 11 swedish dissertations containing the word S100A9.

  1. 1. S100A9 in inflammation

    University dissertation from Lund University, Faculty of Medicine

    Author : Zhifei He; Lunds universitet.; Lund University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; inflammation; oxyclozanide; CD14;

    Abstract : S100A9 is a small (13 kD) cytosolic calcium-binding protein. The protein is mainly expressed in neutrophils and monocytes in human but can also be expressed in other cell types under inflammatory conditions. S100A9 is normally co-expressed with S100A8 and forms S100A8/S100A9 heterodimers. READ MORE

  2. 2. S100A9 in inflammatory disease: a potential target for amelioration

    University dissertation from Lund University, Faculty of Medicine

    Author : Sahar Tahvili; Lunds universitet.; Lund University.; [2018]
    Keywords : Quinoline-3-carboxamide; Myeloid cell; Type 1 diabetes; Cancer; S100A9;

    Abstract : The quinoline-3-carboxamides (Q compounds) are a family of small molecules with immunomodulatory functions that have shown efficacy in various murine models of inflammatory diseases. One such compound has demonstrated antitumor effects in murine models. Q compounds bind to S100A9, thereby preventing its ligation to TLR4 and RAGE. READ MORE

  3. 3. Role of pro-inflammatory S100A9 protein in amyloid-neuroinflammatory cascade in Alzheimer’s disease and traumatic brain injury

    University dissertation from Umeå : Umeå University

    Author : Chao Wang; Umeå universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; ; Alzheimer s disease; Traumatic brain injury; Amyloid; Neuroinflammatory; medicinsk biokemi; Medical Biochemistry;

    Abstract : Background Traumatic brain injury (TBI) is a complex disease with a spectrum of symptoms and disabilities. Over the past decade TBI has become the focus of research due to growing epidemiological and clinical evidences that TBI incidences are strong risk factors for Alzheimer’s disease (AD). READ MORE

  4. 4. Amyloids here, amyloids there…What’s wrong with them?

    University dissertation from Umeå : Umeå University

    Author : Anna Gharibyan; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloids; oligomers; fibrils; cytotoxicity; Alzheimer s disease; Aortic stenosis; S100A9; medicinsk biokemi; Medical Biochemistry;

    Abstract : Amyloid formation is inherent property of proteins which under certain circumstances can become a pathologic feature of a group of diseases called amyloidosis. There are about 30 known human amyloidosis and more than 27 identified proteins involved in these pathologies. READ MORE

  5. 5. Effect of quinoline-3-carboxamides on myeloid cells in inflammation and cancer

    University dissertation from Immunology, Experimental Medical Science, Lund University

    Author : Adnan Deronic; Lunds universitet.; Lund University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Quinoline-3-carboxamide; myeloid cell; inflammation; cancer; peritonitis; mammary carcinoma; fibrosis;

    Abstract : The quinoline-3-carboxamides (Q compounds) are a family of small molecules that ameliorate various types of murine inflammatory autoimmune disease. One such compound has also demonstrated anti-tumor effects in murine tumor models. READ MORE