Search for dissertations about: "S100A9"

Showing result 1 - 5 of 15 swedish dissertations containing the word S100A9.

  2. 1. S100A9 in inflammation

    Author : Zhifei He; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; inflammation; oxyclozanide; CD14;

    Abstract : S100A9 is a small (13 kD) cytosolic calcium-binding protein. The protein is mainly expressed in neutrophils and monocytes in human but can also be expressed in other cell types under inflammatory conditions. S100A9 is normally co-expressed with S100A8 and forms S100A8/S100A9 heterodimers. READ MORE

  4. 2. S100A9 in inflammatory disease: a potential target for amelioration

    Author : Sahar Tahvili; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Quinoline-3-carboxamide; Myeloid cell; Type 1 diabetes; Cancer; S100A9;

    Abstract : The quinoline-3-carboxamides (Q compounds) are a family of small molecules with immunomodulatory functions that have shown efficacy in various murine models of inflammatory diseases. One such compound has demonstrated antitumor effects in murine models. Q compounds bind to S100A9, thereby preventing its ligation to TLR4 and RAGE. READ MORE

  5. 3. Role of pro-inflammatory S100A9 protein in amyloid-neuroinflammatory cascade in Alzheimer’s disease and traumatic brain injury

    Author : Chao Wang; Ludmilla Morozova-Roche; Jonathan Gilthorpe; Øyvind Halskau; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; S100A9; Aβ; Alzheimer s disease; Traumatic brain injury; Amyloid; Neuroinflammatory; medicinsk biokemi; Medical Biochemistry;

    Abstract : Background Traumatic brain injury (TBI) is a complex disease with a spectrum of symptoms and disabilities. Over the past decade TBI has become the focus of research due to growing epidemiological and clinical evidences that TBI incidences are strong risk factors for Alzheimer’s disease (AD). READ MORE

  6. 4. Amyloids here, amyloids there…What’s wrong with them?

    Author : Anna Gharibyan; Ludmilla Morozova-Roche; Tuomas Knowels; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Amyloids; oligomers; fibrils; cytotoxicity; Alzheimer s disease; Aortic stenosis; S100A9; medicinsk biokemi; Medical Biochemistry;

    Abstract : Amyloid formation is inherent property of proteins which under certain circumstances can become a pathologic feature of a group of diseases called amyloidosis. There are about 30 known human amyloidosis and more than 27 identified proteins involved in these pathologies. READ MORE

  7. 5. On neutrophil extracellular traps in leukocyte-dependent inflammation

    Author : Feifei Du; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leukocyte recruitment; Polyphosphate; Neutrophil extracellular traps NETs ; Microparticles; S100A9; Endothelial Cells; Mid1;

    Abstract : .... READ MORE