Search for dissertations about: "S100A9"

Showing result 11 - 15 of 15 swedish dissertations containing the word S100A9.

  2. 11. Avian antibodies applied in particle enhanced turbidimetric immunoassay : Developement of serum/plasma calprotectin immunoassay and its clinical performance as a marker for bacterial infections

    Author : Tom Nilsen; Anders Larsson; Bjørn Steen Skålhegg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; avian antibodies; calprotectin antigen; particle enhanced turbidimetric immunoassay.; Clinical Chemistry; Klinisk kemi;

    Abstract : Calprotectin is a cytosolic protein in the granulocytes, consisting of S100A8 and S100A9. On the site of inflammation, the neutrophils release the cytosol as an inflammatory response. The circulating calprotectin concentration increases and can therefore be used as marker for neutrophil activation and inflammation. READ MORE

  4. 12. Immunometabolic network interactions of the kynurenine pathway in cutaneous malignant melanoma

    Author : Soudabeh Rad Pour; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is the second leading cause of mortality worldwide, and melanoma represents the most aggressive and deadliest form of skin cancer. Despite the various therapeutic approaches, metastatic melanoma is a disease with a poor prognosis. READ MORE

  5. 13. Discovery and validation of protein biomarkers for lung cancer

    Author : Luigi De Petris; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lung cancer is a disease characterized by high incidence and mortality rates as well as by a remarkable resistance to common treatment strategies. Reliable and validated biomarkers could represent a possible breakthrough in the management of this tumor type, by facilitating diagnosis, refining prognosis and providing guidance towards the choice of the most appropriate therapy. READ MORE

  6. 14. Different Aspects of Psoriasis : Comorbidity, Comedication and Disease Biomarkers

    Author : Albert Duvetorp; Oliver Seifert; Jan Söderman; Karin Öllinger; Mats Nilsson; Mona Ståhle; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psoriasis; calgranulin a; calgranulin b; depression; comedication; biomarkers; NBUVB.;

    Abstract : Psoriasis is a common heterogeneous inflammatory disease with its predominant manifestation occurring in the skin. The impact of this disease, however, extends far beyond the skin surface. READ MORE

  7. 15. Studies of in vivo prostate amyloidosis and autoimmune responses towards amyloid structures in neurodegeneration

    Author : Kiran Yanamandra; Ludmilla Morozova-Roche; Dina Raveh; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; amyloidosis; immune reactivity; S100A8 A9; insulin; α-synuclein; Biochemistry; Biokemi; medicinsk biokemi; Medical Biochemistry;

    Abstract : By using multidisciplinary analysis of CA inclusions in prostate glands of patients diagnosed with prostate cancer, we have revealed that their major components are the amyloid forms of S100A8 and S100A9 proteins associated with numerous inflammatory conditions and types of cancer. We have demonstrated that material closely resembling CA can be produced from S100A8/A9 in vitro and shows the characters of amyloids. READ MORE