Search for dissertations about: "SBRT"

Showing result 1 - 5 of 12 swedish dissertations containing the word SBRT.

  2. 1. Searching for the optimal radiotherapy treatment time, dose and fractionation - the role of hypoxia and reoxygenation : A modelling study

    Author : Emely Lindblom; Iuliana Toma-Dasu; Ingmar Lax; Ludvig Paul Muren; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hypoxia; Reoxygenation; SBRT; Fractionation; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : The search for the optimal choice of treatment time, dose and fractionation regimen is one of the major challenges in radiation therapy. Several aspects of the radiation response of tumours and normal tissues give different indications of how the parameters defining a fractionation schedule should be altered relative to each other which often results in contradictory conclusions. READ MORE

  4. 2. lntrafractional motion effects during stereotactic body radiation therapy of lung tumors

    Author : Sebastian Sarudis; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Motion effects; Interplay; SBRT; SGRT; Lung tumors; VMAT; CA;

    Abstract : Abstract: Patient shifts and tumor motions occurring during stereotactic body radiation therapy (SBRT) have been analyzed to determine the related effects on the delivered dose. Methods: 4-dimensional computed tomography series were retrospectively reviewed to characterize respiratory-induced lung tumor motions in 126 patients. READ MORE

  5. 3. Radiobiological end-points for the theoretical evaluation of the effectiveness of carbon ions and photons in treating tumours with dynamic hypoxia

    Author : Antonovic Laura; Iuliana Toma-Dasu; Tatsuaki Kanai; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; OER; hypoxia; LOC; RCR; hypofractionation; SBRT; carbon ion; fractionation; TCP; SF; RCE; RBE; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Tumours are characterised by unorganised vasculature, which often results in hypoxic regions. Hypoxia is a common cause for photon radiotherapy (RT) treatment failure, as hypoxic cells require up to 2-3 times higher doses compared to well-oxygenated cells for the same effect in terms of cell kill. READ MORE

  6. 4. Treatment selection in metastatic renal cell carcinoma : Towards an individualised approach

    Author : Maria Stenman; Magnus Lindskog; Ulrika Harmenberg; Tim Eisen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rcc; renal cell carcinoma; kidney cancer; stereotactic radiotherapy; srt; stereotactic body radiotherapy; sbrt; gamma knife radiosurgery; gkrs; stereotactic radiosurgery; srs; radiotherapy; overall survival; prognostic factor; papillary; Oncology; Onkologi;

    Abstract : Renal cell carcinoma (RCC), a common malignancy worldwide, affects 1200 new patients yearly in Sweden. Metastatic RCC (mRCC) develops in one in three and is commonly incurable. Clear cell histology dominates followed by papillary histology. READ MORE

  7. 5. SBRT of large tumors and tumors located near organs at risk in the thoracic cavity

    Author : Vitali Grozman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Stereotactic Body Radiotherapy (SBRT) is a non-invasive ablative radiation therapy developed at Karolinska University Hospital in the early 90-s. Its basic principles are highly focused inhomogeneous dose load with rapid fall of in the periphery of the target, delivered in few fractions with high-doses per fraction. READ MORE