Search for dissertations about: "SFRP4"

Found 4 swedish dissertations containing the word SFRP4.

  1. 1. Mechanisms of defective insulin secretion in type 2 diabetes

    University dissertation from Islet patophysiology

    Author : Taman Mahdi; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; Insulin secretion; TCF7L2; ADRA2A; KCNQ1; SFRP4; interleukin-1B;

    Abstract : Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. READ MORE

  2. 2. New Insights in Genetic and Epigenetic Mechanisms Involved in Parathyroid Tumorigenesis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lee Starker; Peyman Björklund; Barbra Miller; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parathyroid; yumorigenesis; mutation; exome sequencing;

    Abstract : Primary hyperparathyroidism (pHPT) is a pathology associated with one or multiple hyperfunctioning parathyroid glands.  The disease prevalence occurs in roughly 1-2% of the population primarily post-menopausal women.  The molecular pathology of the disease is poorly understood. READ MORE

  3. 3. Endometrial receptivity and human embryo implantation : in vivo and in vitro studies

    University dissertation from Stockholm : Karolinska Institutet, Dept of Women's and Children's Health

    Author : Sujata Lalit Kumar; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D-endometrial cell construct;

    Abstract : Background: Infertility, one of the common gynaecological disorders, affects 10-15% women in their reproductive years. Despite the advances in assisted reproduction techniques and the best efforts of infertility specialists, implantation rates do not exceed more than 28-30%. READ MORE

  4. 4. Molecular and functional studies on human embryo implantation : targets for infertility and fertility regulation

    University dissertation from Stockholm : Karolinska Institutet, Dept of Women's and Children's Health

    Author : Nageswara Rao Boggavarapu; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Background: An estimated one in four couples globally suffers from infertility or fertility related issues and rate of global infertility is about 10-15%. Despite the best optimization of assisted reproductive technique the pregnancy rate is not more than 30%. READ MORE