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Found 4 swedish dissertations matching the above criteria.

  2. 1. Mechanisms of defective insulin secretion in type 2 diabetes

    Author : Taman Mahdi; Diabetes - öpatofysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; type 2 diabetes; Insulin secretion; TCF7L2; ADRA2A; KCNQ1; SFRP4; interleukin-1B;

    Abstract : Defective insulin secretion from the pancreatic B-cells is a central feature in type 2 diabetes (T2D). There is a strong hereditary component in type T2D, but the underlying pathophysiology remains largely unknown. READ MORE

  4. 2. New Insights in Genetic and Epigenetic Mechanisms Involved in Parathyroid Tumorigenesis

    Author : Lee Starker; Peyman Björklund; Barbra Miller; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parathyroid; yumorigenesis; mutation; exome sequencing;

    Abstract : Primary hyperparathyroidism (pHPT) is a pathology associated with one or multiple hyperfunctioning parathyroid glands.  The disease prevalence occurs in roughly 1-2% of the population primarily post-menopausal women.  The molecular pathology of the disease is poorly understood. READ MORE

  5. 3. Endometrial receptivity and human embryo implantation : in vivo and in vitro studies

    Author : Sujata Lalit Kumar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 3D-endometrial cell construct;

    Abstract : Background: Infertility, one of the common gynaecological disorders, affects 10-15% women in their reproductive years. Despite the advances in assisted reproduction techniques and the best efforts of infertility specialists, implantation rates do not exceed more than 28-30%. READ MORE

  6. 4. Molecular and functional studies on human embryo implantation : targets for infertility and fertility regulation

    Author : Nageswara Rao Boggavarapu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: An estimated one in four couples globally suffers from infertility or fertility related issues and rate of global infertility is about 10-15%. Despite the best optimization of assisted reproductive technique the pregnancy rate is not more than 30%. READ MORE