Search for dissertations about: "SFV"
Showing result 1 - 5 of 26 swedish dissertations containing the word SFV.
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1. Glucosyl transferase gene(s) of temperate bacteriophages SfX and SfV and their role in the modification of the O-antigen of Shigella flexneri
Abstract : Shigella flexneri is the main cause of bacillary dysentery in developing countries with a high attack rate and mortality in young children. Thus developing a S. flexneri vaccine has been given priority by WHO. It has been documented that Shigella lipopolysaccharide (LPS) is highly immunogenic. READ MORE
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2. The dynamic envelope of a fusion class II virus : molecular reorganizations during prefusion stages of Semliki forest virus
Abstract : The aim of this study was to explore a membrane fusion mechanism, prevailing in alphaviruses and known as virus class 11 fusion. The model virus for this mechanism is Semliki Forest virus (SFV) of the alphavirus family. READ MORE
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3. Regulation of autophagy and mTOR during Semliki Forest virus infection
Abstract : Semliki Forest virus (SFV) infection causes dramatic changes to the infected cell. For example, synthesis of most cellular proteins shuts off within 4 hours. The cell launches an antiviral response, forms stress granules and, as we found in the work leading up to this thesis, accumulates autophagosomes. READ MORE
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4. Exploration of host cells during old world alphavirus infection : modulation of RNA granules and the PI3K/AKT pathway
Abstract : As obligate intracellular parasites, viruses have to explore and modulate cellular pathways for their survival. Mechanistic studies of virus–host interactions provide a better understanding of viral infection and cellular responses and help to identify potential targets for therapeutic intervention. READ MORE
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5. Induction of type I interferons and viral immunity
Abstract : Virus-induced type I interferons (IFNα/β) are key mediators of innate immunity and important modulators of adaptive immunity. Early recognition of virus and induction of IFNα/β are important for limiting the spread of the virus. READ MORE