Search for dissertations about: "SIK3"

Found 4 swedish dissertations containing the word SIK3.

  2. 1. LKB1 signaling pathways in adipocytes - Focus on the AMPK-related kinase SIK2

    Author : Emma Henriksson; Proteinfosforylering; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocytes; signal transduction; protein phosphorylation; LKB1; SIK2; SIK3; cAMP;

    Abstract : Adipose tissue does not only store and release energy in response to hormones, it is also known as an endocrine organ, secreting important factors and hormones that influence for example appetite and insulin sensitivity. The association of type 2 diabetes with obesity has been known for quite some time. READ MORE

  4. 2. Protein kinases in hormonal regulation of adipocyte metabolism

    Author : Christine Berggreen; Proteinfosforylering; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adipocyte; PKB; AMPK; SIK3; insulin; catecholamines; lipolysis; lipogenesis; glucose uptake; de novo fatty acid synthesis; A769662; Akti; cAMP;

    Abstract : Abstract Along with liver and muscle tissue, adipose tissue helps maintain normal levels of glucose and lipids in the blood and has a very important role when it comes to storing lipids that can provide whole-body energy. After a meal is ingested, adipocytes take up glucose from the circulation and use it as a substrate for synthesis of new fatty acids (FAs) in a process known as de novo fatty acid synthesis, as well as for synthesis of glycerol. READ MORE

  5. 3. Salt-inducible kinases in adipose tissue

    Author : Johanna Sernevi Säll; Proteinfosforylering; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; salt-inducible kinase; SIK; SIK2; fettväv; fettceller; insulinsignalering; glukosupptag; fetma; insulinresistens; salt-inducible kinase; SIK; SIK2; adipose tissue; adipocytes; insulin signalling; glucose uptake; obesity; insulin resistance;

    Abstract : Obesity, insulin resistance and type 2 diabetes (T2D) are metabolic diseases that increase rapidly in the modern society. The underlying mechanisms are complex and involve both environmental and genetic factors. Adipose tissue is an important organ for maintaining whole body energy homeostasis. READ MORE

  6. 4. Novel aspects of metabolic regulation and inflammation in human adipocytes

    Author : Annie Pettersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The significance of adipose tissue and obesity has been recognized in numerous pathologies. However, the mechanisms behind this connection are not yet completely understood. READ MORE