Search for dissertations about: "SLE"
Showing result 16 - 20 of 162 swedish dissertations containing the word SLE.
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16. Molecular serum portraits - A step towards personalized medicine
Abstract : Antibody microarray technology has the potential for playing a large roll in identifying serological biomarker panels for personalized medicine. The aim of this thesis, based on four original papers, was to investigate if information in the serum proteome could be extracted and used for diagnostic, classificational, prognostic or treatment predictive purposes in a range of diseases. READ MORE
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17. Biomarker Discovery in Autoimmune Diseases using Antibody Microarrays : Targeting Systemic Lupus Erythematosus
Abstract : .... READ MORE
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18. The Genetics of Systemic Lupus Erythematosus : The Specificity of IRF5 to SLE
Abstract : The breakdown of self-tolerance is the main driving force behind susceptibility to SLE. When this occurs, T and B cells are activated in an uncontrolled manner and produce autoantibodies against self fragmented DNA, RNA and sometimes other parts of the cell such as cardiolipin, phosphatidylserine, etc. READ MORE
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19. Inflammation and degeneration in neuropsychiatric SLE
Abstract : .... READ MORE
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20. The genetics of systemic lupus erythematosus : Mapping of susceptibility loci for human SLE
Abstract : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease affecting organs such as skin, jointsand kidneys. Characteristic for the disease is increased production of autoantibodies, in particular against dsDNA. Previous studies of SLE in mouse models and in humans indicate polygenic inheritance and genetic heterogeneity. READ MORE