Search for dissertations about: "SLPI"

Showing result 11 - 15 of 16 swedish dissertations containing the word SLPI.

  1. 11. Development of a protein-free fed-batch process for NS0 cells: studies on regulation of proliferation

    Author : Erika Spens; Lena Häggström; Jean-Louis Goergen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NS0 myeloma cells; protein-free medium; fed-batch; conditioned medium; autocrine growth factors; abortive proliferation; protease activity; aprotinin; gp130; Bioengineering; Bioteknik;

    Abstract : The overall objective of this study was to investigate how NS0 cell proliferation is regulated in protein-free media. The hypothesis was that during the adaptation to growth factor-free media, animal cell lines start to produce their own autocrine growth factors to support proliferation, and after some time in a culture the effects of these factors are lost which results in cessation of proliferation. READ MORE

  2. 12. Studies on a serine peptidase inhibitor locus on human chromosome 20 Characterization of novel genes encoding proteins with WFDC and kunitz domains

    Author : Adam Clauss; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; kunitz; Protase inhibitor; WFDC;

    Abstract : An unlimited number of proteolytic reactions are carried out by enzymes in biological systems. These enzymes are a necessity of life, but they can also be dangerous if they are not controlled. READ MORE

  3. 13. Mucosal immune responses in HIV-1 exposed uninfected individuals

    Author : Taha Hirbod; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The development of HIV vaccines and immunotherapeutics remains hampered by our lack of understanding correlates of immune protection to infection and disease. The major (perhaps only) piece of evidence indicating that long-term, solid resistance to HIV infection is indeed possible comes from HIV exposed yet uninfected individuals (EUI). READ MORE

  4. 14. Infammatory response to hyperbaric trauma. An experimental and clinical study

    Author : Anders Ersson; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; intensive care; Anestesiologi; intensivvård; Complement; Cytokines; NGAL; Secretory leukocyte protease inhibitor; decompression sickness; inflammation; Diving; bubbles;

    Abstract : Reductions in ambient pressure liberates gas in various tissues and can result in decompression illness. In this thesis the patophysiological implications of a blood gas interface resulting from decompression was investigated with reference to the influence on biochemical mediators of inflammation. READ MORE

  5. 15. On airway host defence during allergic inflammation

    Author : Anele Gela; allergologi och palliativ medicin Lungmedicin; []
    Keywords : Asthma; COPD; Antimicrobial peptide; chemokines; immunology;

    Abstract : Asthma is a chronic inflammatory disease of the airways, affecting and disablingapproximately 300 million people worldwide. The inflammatory profile ischaracterized by infiltration of eosinophils, which are a rich source of factors thatare implicated in tissue remodeling. READ MORE