Search for dissertations about: "SNAP"

Showing result 21 - 25 of 54 swedish dissertations containing the word SNAP.

  2. 21. Virus Host Interactions in SARS Coronavirus Infection

    Author : Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). READ MORE

  4. 22. Aspects on the modulation of potassium channels in insulin-producing beta-cells

    Author : Zuheng Ma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : islets of Langerhans; over-stimulation; diazoxide; exocytosis; proteasome; microarray; Kv1.1.;

    Abstract : This thesis attempts to further clarify mechanisms behind the negative effects of overstimulation and the beneficial effect of β-cell rest. For this purpose diazoxide - opener of K+-ATP channels, which reversibly inhibits glucose-induced insulin secretion, was used as a probe. READ MORE

  5. 23. On the mechanisms and physiological function of somatodendritic dopamine release in substantia nigra

    Author : Filip Bergquist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Calcium channels; dopamine release; microdialysis; rotarod; SNARE; striatum; substantia nigra;

    Abstract : Somatodendritic release of neurotransmitters is a neuronal function that is poorly understood in comparison with the more abundant terminal release. This study aimed at characterising somatodendritic dopamine release in substantia nigra in terms of release mechanisms and possible physiological function in motor control. READ MORE

  6. 24. Pharmacological evaluation of the NO/cGMP signalling system

    Author : Anna Asplund Persson; Karl-Erik Andersson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Platelet activation and inhibition are tightly balanced processes, regulated by various endogenous molecules. In this regard, the endothelium plays a key role in mediating inhibition of platelets by releasing nitric oxide (NO) and cAMP-elevating prostaglandins. READ MORE

  7. 25. Changes in neuronal properties induced by neurotropic infections

    Author : Björn Owe-Larsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The nervous system can be the target for various bacterial and viral infectious agents. Certain bacterial toxins have been found to impair specific proteins, such as proteins involved in transmitter release and in the regulation of the cytoskeleton. READ MORE