Search for dissertations about: "SNP interaction"
Showing result 1 - 5 of 44 swedish dissertations containing the words SNP interaction.
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1. The role of genetic variation and DNA methylation in human glucose metabolism and type 2 diabetes
Abstract : The incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. READ MORE
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2. Genes, lifestyle and coronary heart disease risk-epidemiological interaction studies
Abstract : Coronary heart disease (CHD) has multifactorial background involving both genetic and lifestyle factors, but much is still unknown about their interactions. The aim of this thesis was to study interactions focusing on apolipoprotein E (APOE), fat mass and obesity-related (FTO) and ghrelin/obestatin prepropeptide (GHRL) genes, as well as smoking, physical activity and diet. READ MORE
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3. Interaction of genetic susceptibility and traffic-related air pollution in cardiovascular disease
Abstract : This thesis aimed at investigating gene-environment interaction in cardiovascular disease (CVD). A study population of 618 coronary heart disease (CHD) cases (of which 192 first-time acute myocardial infarction (AMI) patients) and 3614 randomly selected population controls was genotyped for genetic variants in genes coding for nitric oxide synthase (NOS) and glutathione s-transferase (GST). READ MORE
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4. Interaction of genetic and environmental factors in childhood asthma and allergy
Abstract : Asthma and allergy are the most common chronic childhood diseases. Their occurrences are influenced by both genetic and environmental factors, although the underlying mechanisms are not fully understood. READ MORE
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5. Family history, genes and gene-environment interaction in risk and prognosis of non-Hodgkin lymphoma
Abstract : Non-Hodgkin lymphoma (NHL) is a heterogeneous group of malignant diseases arising from lymphocytes. There are about 40 subtypes according to the World Health Organizations classification system, differing in morphology, immunophenotype, genetic and/or clinical features. READ MORE