Search for dissertations about: "SNP"

Showing result 21 - 25 of 308 swedish dissertations containing the word SNP.

  1. 21. On the influence of dopamine-related genetic variation on dopamine-related disorders

    Author : Olle Bergman; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; neurodevelopment; amygdala; schizophrenia; Parkinson s disease; social anxiety disorder; ADHD; PITX3; LMX1A; LMX1B; BDNF; DAT; SNP; genes; genetics; BDNF;

    Abstract : Rationale: Dopamine synthesizing neurons are involved in a wide variety of functions. The most prominent dopamine pathways originate in the midbrain. The development, function and survival of these dopaminergic neurons are under the influence of numerous transcription and neurotrophic factors. READ MORE

  2. 22. Quality of life and psychological reactions in women on first line chemotherapy for metastatic breast cancer - Correlations to tumour response and predictive factors

    Author : Helene Svensson; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Recurrence; Health-related quality of life; EORTC QLQ-C30; Metastatic breast cancer; Prognostic factors; Chemotherapy; Toxicity; SNP; Psychological reactions;

    Abstract : Background: Health-related quality of life (HRQoL) is an important endpoint in clinical trials and as an aspect that must be considered in the treatment of patients with metastatic breast cancer. Treatment efficacy and toxicity are important factors for HRQoL, so it is imperative to study the effects of oncological treatment in terms of HRQoL. READ MORE

  3. 23. Approaches for analysis of mutations and genetic variations

    University dissertation from Stockholm : KTH

    Author : Afshin Ahmadian; KTH.; [2001]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LOH; microsatellite; fragment analysis; DNA sequencing; pyrosequencing; cancer; mutation; variation; SNP; allele-specific extension; apyrase; TECHNOLOGY; TEKNIKVETENSKAP;

    Abstract : Detecting mutations and genomic variations is fundamental indiagnosis, isolating disease genes, association studies,functional genomics and pharmacogenomics. The objective hasbeen to use and further develop a variety of tools andtechnologies to analyze these genetic alterations andvariations. READ MORE

  4. 24. Exocytosis in Type 2 Diabetes- Functional and genetic studies of hormone secretion

    University dissertation from Unit of Islet Cell Exocytosis

    Author : Sofia A Andersson; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin; Glucagon; Alpha-cells; Beta-cells; Exocytosis; Capacitance; SNARE; SNAP25; Syntaxin1A; Synaptotagmin; Munc-18 Stxbp1 ; SNP; Expression; miRNA;

    Abstract : Popular Abstract in Swedish Typ 2 Diabetes (T2D) räknas som en folksjukdom i Sverige vilket innebär att den är så vanlig att minst 4 % av befolkningen är drabbad. Förekomsten av diabetes ökar lavinartat över hela världen och man beräknar att så många som 300 miljoner människor har diabetes idag. READ MORE

  5. 25. Gene Mapping in Ficedula Flycatchers

    University dissertation from Uppsala : Universitetsbiblioteket

    Author : Niclas Backström; Uppsala universitet.; [2009]
    Keywords : collared flycatcher; SNP; linkage disequilibrium; genetic map; pedigree;

    Abstract : In order to get full understanding of how evolution proceeds in natural settings it is necessary to reveal the genetic basis of the phenotypic traits that play a role for individual fitness in different environments. There are a few possible approaches, most of which stem from traditional mapping efforts in domestic animals and other model species. READ MORE