Search for dissertations about: "SNPs"

Showing result 1 - 5 of 281 swedish dissertations containing the word SNPs.

  1. 1. Accessing Genetic Variation by Microarray Technology

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Katarina Lindroos; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medical sciences; microarrays; SNPs; minisequencing; four-colour detection; allele frequency; population study; evolutionary biology; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Molekylär medicin; Molecular Medicine;

    Abstract : Microarray technology is a promising approach for the simultaneous analysis of multiple single nucleotide polymorphisms (SNPs), which are the most abundant form of genetic variation. In this thesis enzyme-assisted microarray-based methods were developed to improve the accuracy and genotype discrimination power of the current methods for SNP genotyping. READ MORE

  2. 2. Genome-Wide Studies of Transcriptional Regulation in Human Liver Cells by High-throughput Sequencing

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Madhusudhan Reddy Bysani; Uppsala universitet.; [2013]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ChIP-seq; Transcription factors; Alcoholic steatohepatitis; Genome-wide; GWAS; SNPs;

    Abstract : The human genome contains slightly more than 20 000 genes that are expressed in a tissue specific manner. Transcription factors play a key role in gene regulation. By mapping the transcription factor binding sites genome-wide we can understand their role in different biological processes. READ MORE

  3. 3. Genetic Analyses of Bovid Remains and the Origin of Early European Cattle

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Cecilia Anderung; Uppsala universitet.; [2006]
    Keywords : Molecular genetics; Genetik; Bos taurus; cattle; domestication; aDNA; mtDNA; SNPs;

    Abstract : The aurochs Bos primigenius, extinct since 1627, was the wild progenitor of cattle. It is believed that all European cattle originate from one domestication event in the Near East 10 000 years ago. READ MORE

  4. 4. Wilms' tumor gene 1 in different types of cancer

    University dissertation from Umeå : Umeå University

    Author : Xingru Li; Umeå universitet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WT1; AML; MRD; ccRCC; SNPs; DNA methylation; SCCHN; p63; Clinical Chemistry; klinisk kemi;

    Abstract : The Wilms’ tumor gene 1 (WT1) was first reported as a tumor suppressor gene in Wilms’ tumor. However, later studies have shown the oncogenic properties of WT1 in a variety of tumors. It was recently proposed that WT1 was a chameleon gene, due to its dual functions in tumorigenesis. READ MORE

  5. 5. Human candidate polymorphisms and malaria susceptibility in sympatric ethnic groups, The Fulani and The Dogon of Mali

    University dissertation from Stockholm : Wenner-Grens institut, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Bakary Maiga; Stockholms universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Fulani; Dogon; Blood group; SNPs; IL-4; FcγRIIa; antibody level; molekylär biovetenskap; Molecular Bioscience;

    Abstract : In malaria endemic regions, resistance to malaria constitutes a critical selective pressureon genetic polymorphisms that regulate immune defense and inflammatory pathways.Differences in malaria susceptibility between sympatric ethnic groups have been described inMali. READ MORE