Search for dissertations about: "SP1"

Showing result 11 - 15 of 51 swedish dissertations containing the word SP1.

  2. 11. Pregnancy-specific ß1-glycoprotein (SP1) levels in serum from women with uncomplicated and complicated pregnancies

    Author : Laila Tamsen; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 12. Transcriptional regulation of human nuclear encoded mitochondrial genes

    Author : Ahmed Zaid; Richard Scarpulla; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : Biogenesis of mammalian mitochondria requires the participation of both nuclear and mitochondrial genes. This thesis presents studies that characterize the common features of several nuclear encoded mitochondrial promoter genes and proposes the identity of factors regulating the transcription and responsible for coordinated, constitutive expression of diverse mammalian oxidative phosphorylation (OXPHOS) genes. READ MORE

  5. 13. Mechanisms of p53-mediated intrinsic and extrinsic tumor suppression

    Author : Hai Li; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : p53 is a promising target for cancer therapy. However, the molecular basis of the p53 tumor suppression function remains incompletely understood. Thus, in this thesis, we focused on studies of the molecular mechanisms of p53-mediated tumor suppression. READ MORE

  6. 14. Telomerase activity and its regulation in malignant hematopoietic cells

    Author : Dawei Xu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : hTERT mortalization malignancy activity telomerase regulation;

    Abstract : Telomerase, a multicomponent ribonucleoprotein, synthesizes TTAGGG telomeric repeats essential for the stability and integrity of chromosomes. Most normal human somatic cells exhibit undetectable telomerase activity. READ MORE

  7. 15. Anabolic Androgenic Steroids : Effects on Neuropeptide Systems in the Rat Brain

    Author : Mathias Hallberg; Fred Nyberg; Pierre Le Grevès; James Zadina; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Anabolic androgenic steroids; Nandrolone decanoate; Substance P; NK1 receptor; Substance P 1-7 ; Endopeptidase; Opioids; Calcitonin gene-related peptide; Radioimmunoassay; Autoradiography; Central nervous system; Rats; Biologisk beroendeforskning; Biological research on drug dependence; Biologisk beroendeforskning;

    Abstract : Anabolic-androgenic steroids (AAS) have been used in clinics for decades. The misuse of AAS has previously been attributed merely to sport athletes, taking AAS with intentions to increase muscle mass, enhance physical performance and to improve results in competitions. READ MORE