Search for dissertations about: "SPLICING REACTION"

Showing result 1 - 5 of 11 swedish dissertations containing the words SPLICING REACTION.

  1. 1. Large eddy simulation of combustion using linear-eddy subgrid modeling

    Author : Salman Arshad; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; LES-LEM; splicing; turbulent combustion; super-grid LES-LEM; CFD; linear eddy model; reaction-rate closure; large eddy simulation;

    Abstract : As emissions regulations are getting stricter and efficiency requirements of internal combustion engines (ICE) are increasing, different concepts to improve combustion are being investigated. For example lean stratified premixed combustion, homogeneous charge compression ignition (HCCI), use of more exhaust gas recirculation (EGR) to reduce NOx etc. READ MORE

  2. 2. Biochemical and structural studies of pre-mRNA splicing

    Author : Ingela Wetterberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gene expression; pre-mRNA processing; transcription; in situ; electron tomography;

    Abstract : When eucaryotic genes are expressed, they are transcribed into pre-mRNAs (precursor mRNAs) that need extensive processing before they can be exported from the nucleus as mRNAs and translated into proteins in the cytoplasm. One central processing event is splicing, which means removal of intervening, non-coding sequences, introns and joining of functional sequences, exons. READ MORE

  3. 3. Understanding the Noise : Spliceosomal snRNA Profiling

    Author : Lei Liu Conze; Anders Virtanen; Lars Wieslander; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ncRNA; snRNA; U1; splice site; alternative splicing; high-throughput sequencing; 454; SNP; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : The concept of the gene has been constantly challenged by new discoveries in the life sciences. Recent challenging observations include the high frequency of alternative splicing events and the common transcription of non-protein-coding-RNAs (ncRNAs) from the genome. The latter has long been considered noise in biological systems. READ MORE

  4. 4. Super-grid Linear Eddy Model (SG-LEM): Efficient mode- and regime-independent combustion closure for Large Eddy Simulation (LES)

    Author : Abhilash Murlidharan Menon; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Large Eddy Simulation; Mapping-closure; Lagrangian splicing; Mesh coarse-graining.; Linear Eddy Model;

    Abstract : Next-generation combustion technology such as ‘lean burn’ and HCCI (Homogeneous Charge Compression Ignition) present new challenges for  combustion modelling. The presence of locally varying combustion modes (premixed vs. non-premixed) and regimes (fast/non-fast chemistry vs. READ MORE

  5. 5. Using Minisequencing Technology for Analysing Genetic Variation in DNA and RNA

    Author : Mona Fredriksson; Ann-Christine Syvänen; Aarno Palotie; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; microarray; minisequencing; molecular medicine; single nucleotide polymorphism; stem cell transplantation; whole genome amplification; allelic imbalance; alternative splicing; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ;

    Abstract : In this thesis, the four-color fluorescence tag-microarray minisequencing system pioneered by our group was further developed and applied for analysing genetic variation in human DNA and RNA. A SNP marker panel representing different chromosomal regions was established and used for identification of informative SNP markers for monitoring chimerism after stem cell transplantation (SCT). READ MORE