Search for dissertations about: "SRF"

Showing result 1 - 5 of 14 swedish dissertations containing the word SRF.

  1. 1. Profilin : From the Cell Edge into the Nucleus

    Author : Sara Sadi; Roger Karlsson; Maria Vartiainen; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; profilin; actin; microfilament system; nucleus; SRF; MRTF; MAL; transcription; microtubules; Cell Biology; cellbiologi;

    Abstract : Internal and external signaling dependent changes in cell behavior are directly linked to force-generating remodeling of the actin microfilament system which is juxtaposed to the inside of the plasma membrane. This dynamic filament system is involved in many processes in the cytoplasm and the nucleus of eukaryotic cells. READ MORE

  2. 2. Regulation of gene expression in the vascular wall

    Author : Erik Larsson; Göteborgs universitet; []
    Keywords : smooth muscle; endothelium; angiogenesis; SRF; myocardin; LPP; gene regulation; genetics; microRNA;

    Abstract : Blood vessel growth and function are closely related to a number of pathological conditions, including tumor angiogenesis, wound healing and atherosclerosis. Smooth muscle cells (SMC) and endothelial cells (EC), the two major constituents of the vascular wall, are both characterized by the expression of unique phenotypic marker genes, many of which have vital roles in blood vessel development and disease. READ MORE

  3. 3. New insight into myocardin regulation and function in smooth muscle cells

    Author : Li Liu; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alternative splicing; Contractility; Inflammation; Muscarinic receptor; Myocardin-related transcription factors; Phenotypic modulation; Smooth muscle; SRF; WWTR1; YAP1;

    Abstract : Smooth muscle cells (SMCs) are constituents of hollow inner organs. Their contractile function governs essential physiological functions, such as breathing, eating, blood pressure control, urination, and childbirth. READ MORE

  4. 4. Study of the Superconducting Medium Beta Cavity of the European Spallation Source

    Author : Saeid Pirani; Partikel- och kärnfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SRF elliptical cavity; higher order mode; Qext; field emission; elliptical cavity design; vertical test; Fysicumarkivet A:2020:Pirani;

    Abstract : The thesis explains the design, fabrication, vertical test, higher order mode (HOM) and field emission study of the ESS superconducting medium beta (MB) cavity. The ESS MB cavity is a 6-cell elliptical cavity. The main criteria for a multicell elliptical cavity design are explained. The multicell elliptical cavity fabrication process is discussed. READ MORE

  5. 5. Developmental origin and molecular regulation of vascular smooth muscle cells

    Author : Per Wasteson; Göteborgs universitet; []
    Keywords : smooth muscle cell; aorta; cell origin; lateral plate mesoderm; paraxial mesoderm; lipoma preferred partner; serum response factor; neointimal hyperplasia; angiotensin II; platelet-derived growth factor-B;

    Abstract : Several pathologies of the vascular system have been suggested to be dependent on the smooth muscle cells (SMCs) that build up the vessel wall. Aortic SMCs have been proposed to derive from lateral plate mesoderm. READ MORE