Search for dissertations about: "SSAT"
Showing result 1 - 5 of 6 swedish dissertations containing the word SSAT.
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1. On the Role of Polyamines in Apoptosis
Abstract : Apoptosis is a kind of death that is best described as cellular suicide and it is important for normal tissue homeostasis. The process can be induced by a number of different stimuli and the dying cell goes through a defined pathway terminating in typical biochemical and morphological alterations of the cell. READ MORE
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2. Development and application of advanced electron microscopy techniques for materials in biological systems
Abstract : Theoretically, electron microscopy and scanning probe microscopy offer information on a scale beyond the optical microscope. However, the quality of the micrograph and the obtained information is limited by the sample preparation. READ MORE
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3. Regulation of Polyamine Analogue-Induced Apoptosis in Human Breast Cancer Cells
Abstract : Apoptosis is a defined process for cells to commit suicide through a set of biochemical and morphological cell changes. Activated apoptotic signals converge on the mitochondria, leading to permeabilization of mitochondrial membranes and release of different apoptosis regulatory proteins into the cytosol. READ MORE
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4. Effects of polyamine pool manipulation on genes expressed during the cell cycle
Abstract : The polyamines - putrescine, spermidine and spermine - are polycations found within cells. They have been shown to be essential for optimal cell proliferation and cell survival. Cells maintain their polyamine levels in a well-regulated system involving biosynthesis, catabolism and uptake/excretion. READ MORE
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5. Markers predicting sensitivity to polyamine depletion in human breast cancer cell lines
Abstract : In spite of different treatment strategies today, breast cancer mortality is still high and new treatments are therefore needed. Potential new treatments can be found among the polyamine analogues. Polyamine analogues can be used in cancer treatment as cancer cells have a higher requirement for polyamines than the surrounding healthy tissue. READ MORE