Search for dissertations about: "STD-NMR"

Showing result 1 - 5 of 6 swedish dissertations containing the word STD-NMR.

2. 1. Study of retention mechanisms in Hydrophilic Interaction Chromatography by Nuclear Magnetic Resonance Spectroscopy

   Author : Adel Shamshir; Knut Irgum; Tobias Jonsson; Ngoc Phuoc Dinh; Torgny Fornstedt; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; HILIC; hydrophilic interaction chromatography; adsorption; STD-NMR; saturation transfer difference; retention mechanism; NMRD; solid state-NMR; Analytical Chemistry; analytisk kemi;

   Abstract : This thesis deals with investigations of the retention mechanisms in hydrophilic interaction liquid chromatography (HILIC) using nuclear magnetic resonance spectroscopy. The aims are to understand how the different types of stationary phases can influence the retention of various solutes and the adsorption abilities of solvent on stationary phases. READ MORE

4. 2. Dynamic Systems: Evaluation, Screening and Synthetic Application

   Author : Morakot Sakulsombat; Olof Ramström; Ulrich Lüning; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; constitutional dynamic chemistry; dynamic combinatorial chemistry resolution; dynamic fragment-based approach; dynamic kinetic resolution; dynamic reversible systems; 1H STD-NMR; multicomponent reaction; tandem reaction; Organic chemistry; Organisk kemi;

   Abstract : The research work reported in the thesis deals with the development of dynamic covalent systems and their applications in evaluation and screening of protein-ligands and enzyme inhibitors, as well as in synthetic methodologies. The thesis is divided into four parts as described below. READ MORE

5. 3. Dynamic Sulfur Chemistry : Screening, Evaluation and Catalysis

   Author : Rémi Caraballo; Olof Ramström; Nicolas Giuseppone; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Dynamic combinatorial chemistry; dynamic sulfur chemistry; thioglycoside; mutarotation; disulfide metathesis; hemithioacetal formation; 1H STD-NMR; inhibition; phosphine; Concanavalin A; beta-galactosidase; dynamic drug discovery.; Chemistry; Kemi; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

   Abstract : This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions. In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. READ MORE

6. 4. Structural and Interaction Studies of Bacterial Polysaccharides by NMR Spectroscopy

   Author : Eva-Lisa Nordmark; Göran Widmalm; Sven Müller-Loennies; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacterial polysaccharides; NMR; interaction studies; structural studies; Escherichia coli; Salmonella enteritidis; Streptococcus thermophilus; Propionibacterium freudenreichii; Pseudoalteromonas aliena; P22 TSP; Organic chemistry; Organisk kemi;

   Abstract : An introduction to bacterial polysaccharides and the methods for structural determination are described in the first two parts of the thesis.In a structural elucidation of bacterial polysaccharides NMR experiments are important as is component analysis. A short description of immunochemical methods such as enzyme immunoassays is included. READ MORE

7. 5. Exploring the Molecular Behavior of Carbohydrates by NMR Spectroscopy : Shapes, motions and interactions

   Author : Olof Engström; Göran Widmalm; Anthony S. Serianni; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; NMR relaxation; DNMR; CORCEMA-ST; carbohydrates; caffeine; O-antigen; glycofullerenes; organisk kemi; Organic Chemistry;

   Abstract : Carbohydrates are essential biomolecules that decorate cell membranes and proteins in organisms. They are important both as structural elements and as identification markers. Many biological and pathogenic processes rely on the identification of carbohydrates by proteins, thereby making them attractive as molecular blueprints for drugs. READ MORE