Search for dissertations about: "SURFIN"

Found 2 swedish dissertations containing the word SURFIN.

2. 1. Towards understanding the SURFIN protein family and var genes in Plasmodium falciparum

   Author : Fingani Annie Mphande; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Plasmodium falciparum, the parasite responsible for severe malaria, has been shown to use different protein families for its survival and proliferation within the human host. Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a protein responsible for the cytoadherence of parasitized red blood cells (pRBCs) has been implicated in severe disease. READ MORE

4. 2. Variable surface molecules of the plasmodium falciparum infected erythrocyte and merozoite

   Author : Malin Haeggström; Karolinska Institutet; Karolinska Institutet; []
   Keywords : P.falciparum; infected erythrocytes; transport; Maurer s clefts; antigenic variation; PfEMP1; RIFIN; SURFIN; merozoites; subgroups;

   Abstract : As Plasmodium falciparum parasites matures within the infected erythrocyte (IE) it produces a number of various proteins, which are transported out to the cell surface where they are exposed to the host immune system. To avoid recognition and elimination by the liver and spleen these proteins can undergo antigenic variation, a phenomenon where the parasites switch from expressing one variant to' another, both belonging to the same gene-family. READ MORE