Search for dissertations about: "SVR"

Showing result 1 - 5 of 16 swedish dissertations containing the word SVR.

  1. 1. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Author : Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Abstract : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. READ MORE

  2. 2. Violent recidivism among sexual offenders : risk factors and assessment procedures

    Author : Gabrielle Sjöstedt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Forensic psychiatry; risk assessment; actuarial assessment; PCL-R; VRAG; SVR-20; RRASOR; Static-99; sexual offenders; violent recidivism; criminality;

    Abstract : Background: Assessment and management of risk for violent recidivism to prevent future offending among sexual offenders is an important and challenging task within social, correctional, and forensic mental health services. The overall aim of this thesis was to study the usefulness of various models for the assessment of risk for violent recidivism among sexual offenders in Sweden, and to explore the relationship between individual risk factors and violent recidivism. READ MORE

  3. 3. Long-term clinical, histological and virological outcomes after sustained virologic response in patients with chronic hepatitis C

    Author : Magnus Hedenstierna; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Successful antiviral treatment of chronic hepatitis C (HCV), resulting in Sustained Virologic Response (SVR) has been shown to reduce the risk for liver related complications, hepatocellular carcinoma (HCC) and death. Several studies have also shown that liver histology improves after achieved SVR. READ MORE

  4. 4. Words Don’t Come Easy : Decoding and Reading Comprehension Difficulties in Adolescents with Intellectual Disability

    Author : Karin Nilsson; Henrik Danielsson; Åsa Elwér; Stefan Samuelsson; Kate Cain; Linköpings universitet; []
    Keywords : HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Intellectual disability; Decoding; Reading comprehension; Intellektuell funktionsnedsättning; Avkodning; Läsförståelse;

    Abstract : Individuals with intellectual disability (ID) have difficulties with decoding and reading comprehension. However, studies focussing on why these difficulties occur are very sparse, and the existing literature has found conflicting results. READ MORE

  5. 5. Clinical and molecular features of chronic hepatitis C infection and advanced liver disease

    Author : Nogol Rahbin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to study molecular and clinical aspects of hepatitis C infection (HCV), especially in patients with advanced liver disease. In the first study we investigated whether the use of a second generation contrast agent in ultrasound (US) examinations can improve detection of hepatocellular carcinoma (HCC) and characterisation of focal liver lesions in 49 HCV-infected patients with liver cirrhosis. READ MORE