Search for dissertations about: "SYNTHESIS HETEROCYCLES"

Showing result 1 - 5 of 37 swedish dissertations containing the words SYNTHESIS HETEROCYCLES.

  1. 1. Synthesis of Ring-fused Peptidomimetics : Interacting with Amyloid Fibrils

    Author : Dan E. Adolfsson; Fredrik Almqvist; Anna Linusson; Morten Grötli; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic chemistry; synthesis; peptidomimetics; thiazoline fused 2-pyridones; Alzheimer s disease; Parkinson s disease; Amyloid; Amyloid-beta; alfa-Synuclein; method development; organisk kemi; Organic Chemistry;

    Abstract : Parkinson's and Alzheimer's disease are the two most common neurological disorders in humans. Both conditions involve progressive death of neurons in the central nervous system, decline in bodily functions and eventually (and invariably), death. So far, no cure exists and the available treatments can only ease symptoms. READ MORE

  2. 2. Development of new Catalytic Methods for the Selective Synthesis of Heterocycles

    Author : Stalin Reddy Pathi Pati; Nicklas Selander; Masaharu Nakamura; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; catalysis; indium; heterocycles; Lewis acid; multicomponent reactions; furans; alkynes; organisk kemi; Organic Chemistry;

    Abstract : In the field of organic chemistry, the development of new catalytic methods for the synthesis of complex molecules from simple precursors is a top priority. The main focus of this thesis concerns the diastereoselective synthesis of heterocyclic compounds using main group elements as Lewis acid catalysts. READ MORE

  3. 3. Palladium(0)-Catalysed Carbonylative Multicomponent Reactions : Synthesis of Heterocycles and the Application of Quinolinyl Pyrimidines as Enzyme Inhibitors

    Author : Linda Åkerbladh; Mats Larhed; Luke Odell; Anders Karlén; Lise-Lotte Gundersen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Palladium catalysis; Carbonylation; Multicomponent reactions; Domino reactions; Heterocycles; 4-Quinolones; 2-Aminoquinazolinones; Benzoxazinones; N-Acylguanidines; Type II NADH dehydrogenase; NDH-2;

    Abstract : Palladium-catalysed carbonylative multicomponent reactions have proven useful for the synthesis of structurally diverse compounds. Carbon monoxide serves as an atom-efficient, one-carbon building block, which allows for further structural elaboration of the carbonyl compound. READ MORE

  4. 4. Transformations of Nitrosoarenes and Alkynyl Enones : Selective Synthesis of Nitrogen-Containing Compounds

    Author : Angela van der Werf; Nicklas Selander; Gary A. Molander; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alkynyl enones; catalysis; copper; halogenation; heterocycles; nitrosoarenes; perfluoroalkylation; trifluoromethylation; organisk kemi; Organic Chemistry;

    Abstract : The nitrogen atom plays a unique role in organic chemistry. It is abundantly found in organic materials and is responsible for the activity of many biologically relevant compounds. READ MORE

  5. 5. Synthesis and Characterisation of Conjugated Polymers with High Electron Affinity

    Author : Maria Jonforsen; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; light-emitting diode; solar cell; quinoxaline; conjugated polymer; photodiode; 4-b]pyrazine; pyrido[3; synthesis; photo-oxidation; electron affinity; pyridine;

    Abstract : This thesis describes synthesis and characterisation of conjugated polymers with high electron affinities. Polymers of this type are desired, for example, for use in light-emitting devices or as electron accepting material in photodiodes/solar cells. READ MORE