Search for dissertations about: "SYT-SSX"

Found 3 swedish dissertations containing the word SYT-SSX.

2. 1. The biological role and clinical impact of SYT-SSX fusion gene and IGF-1R in synovial sarcoma

   Author : Yuntao Xie; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Synovial sarcoma; translocation; SYT-SSX; IGF-1R cyclin D1; cell cycle; proliferation; apoptosis.;

   Abstract : Synovial sarcoma, which is a highly malignant soft tissue tumour occurring mainly in young and middle-aged adults, is characterized by the translocation t(X; 18)(p 11.2; q 11.2). READ MORE

4. 2. Detection of fusion genes and fusion proteins in sarcoma : methodological and clinical aspects

   Author : Gunnar Nilsson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Ewing s sarcoma; synovial sarcoma; translocation; fusion gene; fusion protein; diagnosis and prognosis;

   Abstract : Ewing's sarcoma/PNET and synovial sarcoma, all regarded as high-grade tumours, have their peak incidence during the second decade of life, thus affecting children and adolescents. Both tumour types have specific chromosomal translocations, i.e. t(11;22) and t(X;18), respectively, resulting in fusion genes coding for chimeric proteins. READ MORE

5. 3. Morphologic and genetic features of sarcomas : improving diagnosis and exploring biomarkers

   Author : Yifan Zhang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Sarcomas are malignant tumors of soft tissue and bone origin. They are a family of rare but diverse neoplasms which pose clinical challenges due to their heterogeneous properties. READ MORE