Search for dissertations about: "Sahar Roshanbin"
Found 3 swedish dissertations containing the words Sahar Roshanbin.
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1. Characterization of Centrally Expressed Solute Carriers : Histological and Functional Studies with Transgenic Mice
Abstract : The Solute Carrier (SLC) superfamily is the largest group of membrane-bound transporters, currently with 456 transporters in 52 families. Much remains unknown about the tissue distribution and function of many of these transporters. READ MORE
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2. Harnessing the molecular Trojan horse : Evaluating properties of preclinical Aβ immunoPET radioligands for optimized brain delivery via the transferrin receptor
Abstract : With high specificity and selectivity to targets, antibodies are prime candidates for positron emission tomography (PET) radioligands. They do not passively cross the blood-brain barrier which has hindered their development for imaging intrabrain targets, like amyloid-β (Aβ) in Alzheimer’s disease. READ MORE
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3. Visualising neurodegeneration in the living brain : Preclinical evaluation of PET radioligands
Abstract : With an ageing population, the number of people suffering from Alzheimer’s disease (AD) and Parkinson’s disease (PD) escalates yearly. Pathological hallmarks of AD and PD include aggregated proteins and synaptic dysfunction. READ MORE