Search for dissertations about: "Salam Al-Karadaghi"

Found 2 swedish dissertations containing the words Salam Al-Karadaghi.

  1. 1. Refined crystal structures of Zn(II)- and Cu(II)-alcohol dehydrogenase : a comparative study

    Author : Salam al-Karadaghi; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; strukturkemi; Structural Chemistry;

    Abstract : The crystal structure of the ternary complex of horse liver alcohol dehydrogenase (LADH) with the coenzyme NADH and inhibitor dimethyl sulphoxide (DMSO) (space group PI) has been refined by simulated annealing with molecular dynamics and restrained positional refinement using the program system XPLOR. The resulting crystallographic R- factor is 17. READ MORE

  2. 2. Structural and functional properties of transthyretin

    Author : Anders Karlsson; A. Elisabeth Sauer-Eriksson; Salam Al-Karadaghi; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Transthyretin; Amyloidosis; X-ray crystallography; Protein structure; Protein; Structural biology; Strukturbiologi;

    Abstract : The hereditary transthyretin (TTR) amyloidoses are rare, and in severe cases, fatal disorders caused by mutations in the TTR gene. The clinical picture is diverse, involving neuropathies and myopathies, and mainly depends on the causative mutation and the sites and rates of amyloid deposition. READ MORE