Search for dissertations about: "Salivation"

Found 5 swedish dissertations containing the word Salivation.

  2. 1. Salivary glands and oral lesions in diabetes mellitus : an experimental and clinical study with special reference to the influence of metabolic control and duration of the disease

    Author : Carl-Olof Reuterving; Erik Hägg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetes mellitus; salivation; salivary glucose; saliva; submandibular gland; pilocarpine; root surface caries; periodontal disease; alloxan; feeding behavior; rats; humans;

    Abstract : Diabetes mellitus is associated with several clinically significant abnormalities in the oral cavity and salivary glands, the most common being periodontitis, salivary gland enlargement and a sensation of dry mouth. The pre­valence of dental caries in diabetics is mostly reported to be decreased or unaffected. READ MORE

  4. 2. Muscarinic receptors and urinary bladder selectivity : Properties that determine the organ selectivity of compounds

    Author : Staffan Sundquist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; bladder; muscarinic; receptor subtypes; smooth muscle; multivariate; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Urinary bladder contraction is mainly mediated by activation of muscarinic acetylcholine receptors (mAChR). Muscarinic antagonists are often effective in treatment of unstable bladder. The effectiveness of this treatment has often been limited by side effects as dry mouth. READ MORE

  5. 3. Consequences of CYP2D6 polymorphism for the disposition and dynamics of tolterodine : a novel drug in the treatment of urinary bladder overactivity

    Author : Niclas Brynne; Karolinska Institutet; Karolinska Institutet; []
    Keywords : active metabolite; CYP2D6; CYP3A4; disposition; drug interaction; fluoxetine; ketoconazole; metabolic ratio; pharmacokinetics; tolterodine;

    Abstract : The pharmacokinetics and pharmacological effects of tolterodine were studied in man following administration of increasing oral and intravenous single-doses. The influence of metabolic phenotype in extensive and poor metabolizers of debrisoquine was determined. READ MORE

  6. 4. Functional Models in the Search for Pharmacological Treatment of Urinary Incontinence : The Role of Adrenergic, Cholinergic, and Serotonergic Receptors

    Author : Ali-Reza Modiri; Karl-Erik Andersson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Stress incontinence and overactive bladder are disorders with a common symptom, urinary incontinence, which is a serious medical and social handicap. Several neurotransmitters regulate the function of the lower urinary tract, including noradrenaline, acetylcholine, and serotonin. READ MORE

  7. 5. Peripheral nerve glia as multipotent progenitors in craniofacial development

    Author : Maryam Khatibi Shahidi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Craniofacial development is complex. Numerous populations of progenitor cells coordinate activities to produce an array of highly integrated tissues inside the developing head. However, it is not clear how some key multipotent progenitors continue to exist in late developing head compartments. READ MORE