Search for dissertations about: "Sam Xian Jun Cheng"

Found 1 swedish dissertation containing the words Sam Xian Jun Cheng.

2. 1. Functional significance of phosphorylation of rat renal Na+, K+-ATPase by PKA and PKC

   Author : Sam Xian Jun Cheng; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Na ; K -ATPase; protein phosphorylation; cAMP-dependent protein kinase; protein kinase C; site-directed mutagenesis; DNA transfection; isoproterenol; [Ca2 ]i.;

   Abstract : The activity of Na+,K+-ATPase (NKA) is short term regulated by hormones as well as by signalling pathways that involve activation of PKA or PKC, but the mechanism(s) remains unclear. This study was performed to evaluate whether this regulation of NKA occurs via PKA- or PKC-mediated phosphorylation of the NKA a subunit. READ MORE