Search for dissertations about: "Sample fractionation"

Showing result 1 - 5 of 52 swedish dissertations containing the words Sample fractionation.

  2. 1. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity

    Author : Hwanmi Lim; Roger Westerholm; Christoffer Bergvall; Stephen Wise; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; polycyclic aromatic hydrocarbon; PAH; benzo[a]pyrene; B[a]P; carcinogenicity; cancer risk assessment; complex matrix; automation; hyphenation; multidimensional chromatography; two-dimensional; method translation; online fractionation; benz[j]aceanthrylene; B[j]A; relative potency factor; Analytical Chemistry; analytisk kemi;

    Abstract : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. READ MORE

  4. 2. Building a map of the breast cancer proteome - Strategies to increase coverage

    Author : Paolo Cifani; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Quantitative proteomics; Mass-Spectrometry; Cancer; DNA repair; Hypoxia; PTMs; Sample fractionation; Database;

    Abstract : Amongst the various –omics sciences, proteomics has the highest potential for functional characterization and consequently can contribute significantly to the field of cancer research. In particular, the focus of this thesis is on breast cancer. READ MORE

  5. 3. Isotope Ratio and Trace Element Measurements Using Inductively Coupled Plasma – Mass Spectrometry : Method Development and Applications in Environmental Forensics

    Author : Simon Pontér; Anders Widerlund; Hjalmar Laudon; Luleå tekniska universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Isotope ratio measurements; screening analysis; ICP-MS; MC-ICP-MC; multi-tracer studies; fractionation; Environmental Forensics; Tracing; Tillämpad geokemi; Applied Geochemistry;

    Abstract : Environmental Forensics is a scientific methodology developed for identifying sources, the timing of release, and transport pathways for potentially hazardous environmental contaminants. It combines a variety of analytical methods with principles derived from disciplines such as chemistry, geology, geochemistry, hydrogeology, and statistics, with the purpose to provide objective scientific and legal conclusions on the source and/or time of a contaminant release. READ MORE

  6. 4. Purification Processes for Complex Biomacromolecules

    Author : Hans Blom; Helena Grennberg; Mats Lundgren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Chromatography; enzymes; mucins; fractionation; plasmid DNA; analysis; clarification; process design; Chemistry with specialization in Surface Biotechnology; Kemi med inriktning mot ytbioteknik;

    Abstract : This thesis details various techniques and considerations for the purification of complex biomacromolecules. Initially an α-mannosidase from babaco fruit was purified using anion exchange-, lectin affinity- and size exclusion chromatography. READ MORE

  7. 5. Mass spectrometry based proteomic strategies applied in the study of central nervous system derived cells

    Author : Annika Thorsell; Göteborgs universitet; []
    Keywords : proteomics; mass spectrometry; protein identification; protein quantitation; fractionation;

    Abstract : This thesis focuses on evaluation, improvement and development of mass spectrometry based proteomic strategies for identification and quantitation of proteins. Development of such strategies is important to achieve a better understanding of regulatory mechanisms of individual cell types, both during normal development and during the onset and progression of diseases. READ MORE