Search for dissertations about: "Schwann cell"
Showing result 11 - 15 of 52 swedish dissertations containing the words Schwann cell.
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11. Sensory neuronal protection & improving regeneration after peripheral nerve injury
Abstract : Peripheral nerve trauma is a common cause of considerable functional morbidity, and healthcare expenditure. Particularly in the ~15% of injuries unsuitable for primary repair, standard clinical management results in inadequate sensory restitution in the majority of cases, despite the rigorous application of complex microsurgical techniques. READ MORE
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12. Mechanisms and improvements of cell transplantation for nerve repair
Abstract : Trauma to the nervous system is a frequent clinical problem and new approaches to nerve repair are required. Autologous cell transplantation together with a suitable scaffold material could be used to create a bio-active artificial nerve graft to enhance regeneration. READ MORE
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13. Tendon autografts for bridging nerve defects
Abstract : A new method, where a tendon segment – a tendon autograft – was used as graft material for peripheral nerve reconstruction, was developed. Defects, 10-15 mm long, in rat sciatic nerves were bridged by various modifications of tendons. READ MORE
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14. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration
Abstract : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. READ MORE
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15. Mesenchymal stem cells for repair of the peripheral and central nervous system
Abstract : Bone marrow-derived mesenchymal stem cells (MSC) have been shown to provide neuroprotection after transplantation into the injured nervous system. The present thesis investigates whether adult human and rat MSC differentiated along a Schwann cell lineage could increase their expression of neurotrophic factors and promote regeneration after transplantation into the injured peripheral nerve and spinal cord. READ MORE