Search for dissertations about: "Schwann cell"

Showing result 16 - 20 of 52 swedish dissertations containing the words Schwann cell.

  2. 16. Stem cells for nerve repair and prevention of muscle atrophy

    Author : Dominique Schaakxs; Paul Kingham; Mikael Wiberg; Daniel Kalbermatten; Christine Radtke; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipose stem cells; biomaterial; muscle; nerve injury; neuromuscular junction; regeneration; cell research; cellforskning; Medical Cell Biology; medicinsk cellbiologi;

    Abstract :   Peripheral nerve injury (PNI) is common and despite modern microsurgical techniques of repair, functional restoration is always incomplete. This results in impaired sensation and reduced motor function alongside pain and cold intolerance. READ MORE

  4. 17. Biosynthetic conduits and cell transplantation for neural repair

    Author : Jonas Pettersson; Lev Novikov; Liudmila Novikova; Mikael Wiberg; Lars Dahlin; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinal cord injury; Peripheral nerve injury; Nerve graft; Biosynthetic conduit; Nerve tissue engineering; Neural prosthesis; Neuroscience; Neurovetenskap; neurologi; Neurology; neurokirurgi; Neurosurgery;

    Abstract : Spinal cord injury results in complete failure of the central neurons to regenerate and is associated with cyst formation and enlargement of the trauma zone. In contrast to the spinal cord, axons in the injured peripheral nerve have the capacity to undergo some spontaneous regeneration. READ MORE

  5. 18. Prion processing and propagation in neuronal and dendritic cell culture models

    Author : Katarina M Luhr; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prion; scrapie; cathepsin; processing; IFN-gamma; DRG; dendritic cell; cytokine;

    Abstract : Prion diseases are rare neurodegenerative diseases, associated with a conversion of a normal cellular protein, PrPC, into its misfolded and partial protease resistant isoform, PrPSc. These diseases affect both animals and humans and are unique since they can not only be genetic and sporadic, but also transmissible. READ MORE

  6. 19. Regeneration of the auditory nerve : a cell transplantation study

    Author : Björn Palmgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Since in mammals, the hair cells or the spiral ganglion neurons (SGNs) in the inner ear do not regenerate, damage to these cells is an irreversible process. Presently the only aid for patients with severe to profound hearing impairment due to damaged hair cells is a cochlear implant (CI). READ MORE

  7. 20. Repair and Reconstruction of Peripheral Nerve Injuries. Treatment with G-CSF and Stromal Vascular Fraction

    Author : Hanna Frost; Malmö Handkirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; peripheral nerve injuries; nerve regeneration; reconstructive surgical procedures; diabetes mellitus; rat sciatic nerve; granulocyte colony-stimulating factor; stromal vascular fraction; electrospinning; rats; Schwann cells;

    Abstract : While surgery is a cornerstone in treatment of peripheral nerve injuries, it is not a comprehensive approach, and outcome is unsatisfactory, especially sensory function. The present aim was to translate recent findings about stem- and progenitor cells to improve regenerative outcome, where the cells have to be autologous, available within the same surgical procedure, and minimally manipulated. READ MORE