Search for dissertations about: "Schwann cell"
Showing result 21 - 25 of 52 swedish dissertations containing the words Schwann cell.
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21. Auxiliary Cells for the Vascularization and Function of Endogenous and Transplanted Islets of Langerhans
Abstract : Type 1 diabetes develops through the progressive destruction of the insulin-producing beta-cells. Regeneration or replacement of beta-cells is therefore needed to restore normal glucose homeostasis. Presently, normoglycemia can be achieved by the transplantation of whole pancreas or isolated islets of Langerhans. READ MORE
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22. Nerve gap repair by the use of artificial conduits and cultured cells
Abstract : Peripheral nerve injuries are often associated with loss of nerve tissue and require autologous nerve grafts to provide a physical substrate for axonal growth. This thesis investigates the use of fibrin as both a tubular conduit to guide nerve regeneration and also as a matrix material to suspend various regenerative cell types within/on poly-3-hydroxybutyrate (PHB) nerve conduits. READ MORE
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23. Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins
Abstract : The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. READ MORE
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24. Phospholipase A2 in nerve injury and axonal outgrowth
Abstract : This thesis deals with processes coupled to injury in the peripheral nervous system (PNS), with a general aim to investigate the role of phospholipase A2 (PLA2) enzymes in axonal outgrowth. The axonal outgrowth of dorsal root ganglia (DRG) neurons in vitro was reduced by several different inhibitors of PLA2 activity and enhanced by an activator of this enzyme. READ MORE
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25. Cell-matrix interactions in neuronal regeneration : focus on integrins and laminins
Abstract : The central and peripheral nervous system (CNS and PNS, respectively) differ in their ability to regenerate after injury. This difference has been attributed both to intrinsic differences in the properties of the neurons and to the extracellular environment. READ MORE