Search for dissertations about: "Sebastian Jobjörnsson"

Found 2 swedish dissertations containing the words Sebastian Jobjörnsson.

  1. 1. On the Optimisation and Regulation of Clinical Trials

    University dissertation from ; Chalmers tekniska högskola; Gothenburg

    Author : Sebastian Jobjörnsson; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; decision theory; Bayesian statistics; optimal stopping.; clinical trials; subgroup analysis; drug regulation;

    Abstract : The basic premise of this thesis is that Bayesian Decision Theory (BDT) can and should be used to solve clinical trial design problems. While the flexibility of the framework allows for accommodating a great variety of situations, it also requires an explicit consideration of the gains and costs associated with the trial. READ MORE

  2. 2. Optimisation of Clinical Trials using Bayesian Decision Theory

    University dissertation from Gothenburg : Chalmers University of Technology

    Author : Sebastian Jobjörnsson; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; decision theory; drug regulation; pharmaceutical R D; Bayesian statistics; subgroup analysis; clinical trials; health economics; multiple testing;

    Abstract : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. READ MORE