Search for dissertations about: "Sebastian Leidel"

Found 1 swedish dissertation containing the words Sebastian Leidel.

2. 1. Influence of wobble uridine modifications on eukaryotic translation

   Author : Hasan Tükenmez; Anders Byström; Tracy Nissan; Sebastian Leidel; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES;

   Abstract : Elongator is a conserved six subunit protein (Elp1p-Elp6p) complex that is required for the formation of ncm5 and mcm5 side chains at wobble uridines in transfer RNAs (tRNAs). Moreover, loss-of-function mutations in any gene encoding an Elongator subunit results in translational defects and a multitude of phenotypic effects. READ MORE