Search for dissertations about: "Septic shock thesis"

Showing result 1 - 5 of 64 swedish dissertations containing the words Septic shock thesis.

  1. 1. Experimental septic shock : a study on splanchnic oxygen delivery and consumption, tissue oxygenation, some aspects of hepatic glucoregulatory enzyme, and cytochrome P450 activities

    Author : Ib Rasmussen; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  2. 2. Strain echocardiography in the critically ill patient : Studies in patients with septic shock and subarachnoid haemorrhage

    Author : Keti Dalla; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Strain echocardiography in ICU patients; Left ventricle; Right ventricle; Septic shock; Subarachnoid haemorrhage; Norepinephrine;

    Abstract : In this thesis, strain echocardiography by two-dimensional speckle tracking imaging (2D-STI), was used for the evaluation of left ventricular (LV) and right ventricular (RV) function in critically ill patients with septic shock and subarachnoid haemorrhage. The aims were to: 1) investigate the value of strain echocardiography for the early detection of LV and RV dysfunction not diagnosed with conventional echocardiography in severe sepsis and septic shock, 2) to study the effects of norepinephrine on RV systolic function and pulmonary haemodynamics in patients with norepinephrine-dependent septic shock 3) evaluate the use of strain echocardiography for detection of myocardial injury in patients with subarachnoid haemorrhage (SAH) and 4) study the impact of general anaesthesia and positive pressure ventilation (PPV) on RV and LV myocardial longitudinal strain. READ MORE

  3. 3. C5a Receptor Expression in Severe Sepsis and Septic Shock

    Author : Mia Furebring; Jan Sjölin; Per Folllin; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; C5a receptor; granulocyte; severe sepsis; septic shock; chemotaxis; anti-C5a treatment; ex vivo incubation; C5a; interleukin-8; LPS; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Abstract : In patients with sepsis, the activation of the cascade systems, for example the complement system with the generation of C5a, is followed by a state of immunosuppression with impaired bactericidal capacity caused by suppression of the neutrophil granulocytes. To inhibit the C5a-induced systemic inflammatory and the following anti-inflammatory responses, different anti-C5a strategies have been successful in experimental models of sepsis. READ MORE

  4. 4. Cardiac dysfunction in septic shock : Observational studies on characteristics and outcome

    Author : Lina De Geer; Christina Eintrei; Anna Oscarsson Tibblin; Jan Engvall; Else Tønnesen; Linköpings universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Background: Cardiac dysfunction is a well-known complication of sepsis, but its characteristics and consequences, especially on a longer term, remain unclear. The aim of this thesis was to study the characteristics and the implications of cardiac dysfunction for outcome in intensive care unit (ICU) patients with septic shock. READ MORE

  5. 5. Nitric oxide production by the intestinal mucosa during hypoperfusion

    Author : Johan Snygg; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nitric oxide; nitric oxide synthase; intestinal epithelium; hemorrhagic shock; cardiac tamponade; septic shock; lower body negative pressure; splanchnic circulation; substrate; laser Doppler;

    Abstract : The present thesis is based on the concept that gastrointestinal blood hypoperfusion is a common phenomenon associated with critical illness. Furthermore, the development of the multiple organ dysfunction syndrome (MODS) is proposed to be initiated by gastrointestinal mucosal barrier dysfunction, allowing intestinal luminal contents to penetrate into the tissue and activate a systemic inflammatory response. READ MORE