Search for dissertations about: "Sergi Tosal Castaño"

Found 1 swedish dissertation containing the words Sergi Tosal Castaño.

2. 1. A molecular chaperone that governs membrane contact sites and lipid metabolism

   Author : Sergi Tosal Castaño; Sabrina Büttner; W. Mike Henne; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Yeast; nucleus-vacuole junctions; proteostasis; unfolded protein response; fatty acid elongation; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Transmembrane proteins represent almost one third of the total cellular proteome, and the majority of them requires translocation into the endoplasmic reticulum (ER) to be folded, sorted and transported to their final subcellular destination. High translational rates during exponential cell growth result in a massive influx of immature proteins into the ER, requiring rapid and accurate folding. READ MORE