Search for dissertations about: "Serological thesis"

Showing result 16 - 20 of 178 swedish dissertations containing the words Serological thesis.

  2. 16. Serological classification and genetic characterization of clinical isolates of Neisseria gonorrhoeae

    Author : Marianne Bäckman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neisseria gonorrhoeae; serotyping; antibiotic susceptibility; plasmid; pilC; auxotyping; fingerprinting; geographical origin;

    Abstract : Neisseria gonorrhoeae is the etiologic agent of gonorrhoea, one of the oldest and most widespread of human infections. The development of methods to characterize the bacterium is of central importance in the control of the disease. One aim of this thesis was to evaluate serotyping of N. READ MORE

  4. 17. Bifunctional ADAPTs: Opportunity for serological Half-life extension and Targeted therapy

    Author : Andreas Wisniewski; Sophia Hober; Masood Kamali-Moghaddam; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABD; ADAPT; Autoimmune diseases; Cancer; Half-life extension; HRP; Phage Display; Protein Engineering; Targeted therapy; Biotechnology; Bioteknologi;

    Abstract : Small engineered scaffold proteins (ESPs) gain more and more popularity as biological drugs, due to their specificity and applicability in diagnostics and therapy. Thanks to their high stability, low immunogenicity and low production cost, they present themselves as a promising alternative to the market-leading antibodies. READ MORE

  5. 18. Detection of Chlamydia trachomatis and Mycoplasma genitalium by genetic and serological methods

    Author : Margaretha Jurstrand; Hans Fredlund; Erik Kihlström; Örebro universitet; []
    Keywords : Chlamydia trachomatis; genotyping; contact tracing; sexually transmitted diseases; Mycoplasma genitalium; PCR; serology; MEDICINE; MEDICIN; Medicin; Medicine;

    Abstract : Chlamydia trachomatis infections are associated with a spectrum of clinical diseases including urethritis, prostatitis and epididymitis among men and cervicitis and pelvic inflammatory disease (PID), with an increased risk of infertility and ectopic pregnancy (EP), among women. In the search for other pathogens causing urethritis, Mycoplasma genitalium was isolated from urethral specimens from two men with acute urethritis (1980). READ MORE

  6. 19. Staphylococcus aureus bacteremia. Serological findings, phenotypic and genotypic characteristics of S. aureus strains

    Author : Ulf Ryding; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infections; Infektioner; serology; collagen binding protein.; Staphylococcus aureus bacteremia;

    Abstract : The diagnosis of S. aureus infections is most often based on culture of the organism from various body sites. However, cultures could be false negative due to e.g. READ MORE

  7. 20. Advanced molecular tools for diagnostic analyses of RNA and antibodies in situ and in solution

    Author : Mengqi Wang; Ulf Landegren; Anders Ståhlberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Homogenous serological assay; PCR-based antibody detection; Proximity extension assay; SARS-CoV-2 antibody; Extracellular vesicles; Proximity barcoding assay; in situ superRCA; mutant transcript;

    Abstract : Advanced molecular diagnostics uses in vitro biological assays to detect nucleic acids or proteins even in low concentrations across samples, allowing for the identification of biomarkers, monitoring the course of the disease over time, and selection of appropriate therapy. In this thesis, I focus on development and early applications of several molecular tools of expected value in research, and eventually also clinically. READ MORE