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Showing result 1 - 5 of 51 swedish dissertations matching the above criteria.

2. 1. Severe traumatic brain injury : clinical course and prognostic factors

   Author : Maud Stenberg; Britt-Marie Stålnacke; Richard Levi; Jan Lexell; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe traumatic brain injury; outcome; rehabilitation; prognosis; rehabiliteringsmedicin; Rehabilitation Medicine;

   Abstract : Traumatic brain injury (TBI) constitutes a major health problem and is a leading cause of long-term disability and death. Patients with severe traumatic brain injury, S-TBI, comprise a heterogeneous group with varying complexity and prognosis. READ MORE

4. 2. On severe traumatic brain injury : aspects of an intra cranial pressure-targeted therapy based on the Lund concept

   Author : Magnus Olivecrona; Lars-Owe D Koskinen; Bertil Romner; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; severe traumatic brain injury; ICP targeted therapy; ICP; hemicraniectomy; seizures; prostacyclin; microdialysis; outcome; S100B; NSE; Neurosurgery; Neurokirurgi;

   Abstract : Severe Traumatic Brain Injury (sTBI) is a major cause of mortality and morbidity. At the Department of Neurosurgery Umeå University Hospital subjects with sTBI are treated with an intracranial pressure (ICP) guided therapy based on physiological principles, aiming to optimise the microcirculation of the brain so avoiding secondary brain injuries. READ MORE

5. 3. Brain Tissue Oxygenation in Traumatic Brain Injury : Experimental and Clinical Studies

   Author : Karlis Purins; Anders Lewén; Per Enblad; Oliver Sakowitz; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Brain tissue oxygenation; Cerebral metabolism; Traumatic brain injury; Cerebral ischemia; Threshold levels; Neurovent-PTO; Microdialysis; Neurosurgery; Neurokirurgi;

   Abstract : Traumatic brain injury (TBI) is a major cause of death and disability. TBI is frequently followed by cerebral ischemia which is a great contributor to secondary brain damage. The main causes of cerebral ischemia are pathophysiological changes in cerebral blood flow and metabolism. READ MORE

6. 4. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

   Author : Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

   Abstract : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. READ MORE

7. 5. Clinical Consequences of Axonal Injury in Traumatic Brain Injury

   Author : Sami Abu Hamdeh; Niklas Marklund; Per Enblad; Lars Hillered; Andreas PhD Unterberg MD; Uppsala universitet; []
   Keywords : Traumatic brain injury; diffuse axonal injury; intracranial pressure; magnetic resonance imaging; amyloid-beta; tau; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI), mainly caused by road-traffic accidents and falls, is a leading cause of mortality. Survivors often display debilitating motor, sensory and cognitive symptoms, leading to reduced quality of life and a profound economic burden to society. READ MORE