Search for dissertations about: "Severe traumatic brain injury"

Showing result 16 - 20 of 51 swedish dissertations containing the words Severe traumatic brain injury.

  1. 16. Cellular Reactions and Behavioral Changes in Focal and Diffuse Traumatic Brain Injury : A Study in the Rat and Mouse

    Author : Sara Ekmark Lewén; Lars Hillered; Niklas Marklund; Anders Lewén; Mårten Risling; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Astrocytes; Inflammatory response; Multivariate concentric square field test; Morris water maze; Exploratory behavior; Risk taking; Functional outcome.; Neurosurgery; Neurokirurgi;

    Abstract : Traumatic brain injury (TBI) is a severe condition and a major cause of death and disability. There is no pharmacological treatment available in clinical practice today and knowledge of brain injury mechanisms is of importance for development of neuroprotective drugs. READ MORE

  2. 17. Outcome after modern neurosurgical care and formalised rehabilitation following severe brain injury

    Author : Ann Sörbo; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; outcome; severe brain injury; life satisfaction; early formalised rehabilitation; change over time; decompressive craniectomy; long-term follow-up;

    Abstract : Aims: The overall aims were to evaluate the results of the treatment concepts for severe brain injury including decompressive craniectomy (DC), early rehabilitation and long-term follow-up, primarily according to the psychosocial consequences of the brain damage and life satisfaction. The first study was a cross-sectional study to assess and compare the consequences for outcome for two groups with severe traumatic brain injury (TBI) or subarachnoid haemorrhage (SAH), one group that received early, long-term formalised rehabilitation and the other that received late or no formalised rehabilitation. READ MORE

  3. 18. On evolution of intracranial changes after severe traumatic brain injury and its impact on clinical outcome

    Author : Lukas Bobinski; Lars-Owe Koskinen; Magnus Olivecrona; Peter Lindvall; Marklund Niklas; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe traumatic brain injury; ICP targeted therapy; ICP; decompressive craniectomy; S100B; NSE; cranioplasty; neurokirurgi; Neurosurgery;

    Abstract : Severe traumatic brain injury (sTBI) is a cause of death and disability worldwide and requires treatment at specialized neuro-intensive care units (NICU) with a multimodal monitoring approach. The CT scan imaging supports the monitoring and diagnostics. The level of S100B and neuron specific enolase (NSE) reflects the severity of the injury. READ MORE

  4. 19. Prediction value of genetic and neuromarkers in blood and liquor in patients with severe traumatic brain injury

    Author : Martin Öst; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; outcome; NFL; GFAP; tau; β-amyloid; apolipoprotein E; biochemical neuromarkers;

    Abstract : Background: Severe traumatic brain injury (sTBI) is the most common cause of mortality in young adults. sTBI induces variable brain damage, invisible in Computer Tomographic scans early post-trauma. Further, neurology is difficult to evaluate in sedated patients. READ MORE

  5. 20. Long-term outcome after traumatic brain injury : studies of individuals from northern Sweden

    Author : Lars Jacobsson; Jörgen Borg; Luleå tekniska universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health Science; Hälsovetenskap;

    Abstract : As traumatic brain injury (TBI) is as one of the major causes of long-term disability, there is an increasing interest in the long-term outcome of TBI. The overall aim of this thesis was to increase our knowledge and understanding of the situation for individuals many years post injury, with regard to demographics, injury characteristics and primary outcome, long-term functioning and disability, health-related quality of life, life satisfaction, self-appraisal of the impact of the TBI and sense of coherence. READ MORE