Search for dissertations about: "Severe traumatic brain injury"
Showing result 21 - 25 of 51 swedish dissertations containing the words Severe traumatic brain injury.
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21. The role of reactive oxygen species in traumatic brain injury : Experimental studies in the rat
Abstract : Traumatic brain injury (TBI) is a major cause of mortality and disability. As common sequelae in survivors of TBI are disabling functional, emotional and cognitive disturbances, improved treatment of TBI patients is urgently needed. At present, no neuroprotective pharmacological treatment exists. READ MORE
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22. Pressure autoregulation of cerebral blood flow in traumatic brain injury and aneurysmal subarachnoid hemorrhage
Abstract : The ability of the brain to keep a stable and adequate cerebral blood flow (CBF) independently of fluctuations in systemic blood pressure is referred to as cerebral pressure autoregulation (CPA). When the brain is injured by trauma or hemorrhage, this ability may be impaired, leaving the brain vulnerable to events of high or low blood pressure. READ MORE
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23. Pathophysiological characterization of traumatic brain injury using novel analytical methods
Abstract : Severity of traumatic brain injury is usually classified by Glasgow coma scale (GCS) as “mild”, "moderate" or "severe’, which does not capture the heterogeneity of the disease. According to current guidelines, intracranial pressure (ICP) should not exceed 22 mmHg, with no further recommendations concerning individualization or tolerable duration of intracranial hypertension. READ MORE
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24. Interplay between blood-brain barrier disruption and neuroinflammation following severe traumatic brain injury
Abstract : A severe traumatic brain injury (TBI) holds deleterious consequences for the afflicted, its next-of-kin and society. Still today, prognosis is semi-desolate. One explanation for this might be pathophysiological processes ensuing the primary trauma that are but indirectly targeted for treatment. READ MORE
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25. Severe Head Injury. Evaluation of Acute Treatment and Rehabilitation
Abstract : Mortality after severe head injury can be considerably reduce with a therapy using physiological principles for brain volume regulation and preserved microcirculation, with the main purpose of restricting the rise in ICP to reasonable levels simultaneously with preservation of adequate blood supply. This study shows that the ?Lund Concept? can reduce mortality in patients with severe traumatic brain lesions from 47% to 8%. READ MORE