Search for dissertations about: "SiaT"

Found 3 swedish dissertations containing the word SiaT.

  2. 1. Structural and Functional Studies of Membrane Proteins For Future Development of Antimicrobial Drugs

    Author : Elin Dunevall; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Sialic acid transporters; SiaT; MraY; Tunicamycin; Antibiotic resistance;

    Abstract : Antibiotic resistance is a world-wide occurring problem which threatens human health. Without development of any new and effective antibiotics, the rapid growth of antibiotic-resistant bacterial infections could put society in a situation resembling the pre-antibiotic era when a simple lung infection could kill a human being. READ MORE

  4. 2. Structural Insight into the Bacterial Sialic Acid Catabolic Pathway

    Author : Rhawnie Caing Carlsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sialic acid; bacterial catabolic pathway;

    Abstract : A genetically diverse community of commensal and pathogenic bacteria thrive in the digestive system and urogenital tracts of animals. Many of these bacteria forage sialic acid from mucosal cell surfaces. READ MORE

  5. 3. Design, synthesis and evaluation of bacterial sialic acid uptake inhibitors

    Author : Tiago Bozzola; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Sialic Acid; antibacterial agents; Medicinal Chemistry; Synthesis; uptake inhibitors;

    Abstract : Antibiotic resistance is a major threat for our society and finding novel antibacterial therapies is of greatimportance. In this thesis, we investigate bacterial sialic acid uptake inhibitors as a novel antibacterial approach.Bacteria do not biosynthesise sialic acid and therefore harvest it from the host. READ MORE