Search for dissertations about: "Sibling donor"

Showing result 1 - 5 of 17 swedish dissertations containing the words Sibling donor.

2. 1. Allogeneic stem cell transplantation : patients’ and sibling donors’ perspectives

   Author : Annika M Kisch; Malmö högskola; []
   Keywords : Allogeneic haematopoietic stem cell transplantation; Confidentiality; Information and care model; Quality of life; Perspectives; Sibling donor; Stem cell donation;

   Abstract : Allogeneic haematopoietic stem cell transplantation (hereafter HSCT) is an established treatment which offers a potential cure for a variety of diseases, mainly haematological malignancies. However, the treatment is also associated with significant risks of acute complications and late side effects, including mortality. READ MORE

4. 2. HLA and KIR gene polymorphism in hematopoietic stem cell transplantation

   Author : Marie Schaffer; Karolinska Institutet; Karolinska Institutet; []
   Keywords : HLA; KIR; NK cells; hematopoietic stem cell transplantation; unrelated donor;

   Abstract : The major histocompatibility complex (MHC) in humans known as the Human Leukocyte Antigens (HLA) is localised to the short arm of chromosome six. The HLA class 1 antigens, HLA-A, -B and -C are highly polymorphic glycoproteins expressed on the cell surface of most nucleated cells in the body. READ MORE

5. 3. Outcome after allogeneic stem cell transplantation with special reference to non-malignant disorders, chimerism and graft cell composition

   Author : Petter Svenberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The outcome for patients undergoing allogeneic stem cell transplantation (HSCT), a treatment for several severe malignant and non-malignant disorders with hematopoietic origin, is a balancing act between beneficiary effects and risk factors. Treatment success is still limited by excessive immune response, such as graft-versus-host–disease (GVHD) and graft failure (GF), or the lack thereof as in malignancy relapse or severe infections. READ MORE

6. 4. Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity

   Author : Åsa Gustafsson Jernberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Children; CTL; EBV; Graft-versus-leukaemia; Stemcell transplantation; unrelated;

   Abstract : Allogeneic stem cell transplantation (SCT) can cure leukaemia, aplastic anaemia, and some inborn errors of metabolism and immunodeficiencies in children. As only 113 of patients who need SCT have an HLA-identical sibling, the use of alternative donors has increased, to over 50% of all paediatric SCTs at our centre. READ MORE

7. 5. Antitumor effect in allogeneic hematopoietic stem cell transplantation in patients with solid cancer

   Author : Réka Conrad; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Allogeneic hematopoietic stem cell transplantation (HSCT) has been presented as a promising immunotherapy not only against hematological malignancies but also against solid tumors. Different solid tumors such as renal cell, breast, colon, prostate and advanced primary liver cancer have been treated with HSCT at our center. READ MORE