Search for dissertations about: "Signal Transduction"

Showing result 6 - 10 of 387 swedish dissertations containing the words Signal Transduction.

  2. 6. Mechanisms of Integrin Signal Transduction

    Author : Anne Stefansson; Staffan Johansson; Annika Armulik; Björn Öbrink; Uppsala universitet; []
    Keywords : Cell biology; Integrin; Integrin signalling; PI3K; Akt PKB; Integrin transmembrane domain; cell spreading; Cellbiologi;

    Abstract : Integrins are a protein family of cell surface receptors, expressed in all cell types in the human body, except the red blood cells. Besides their importance in mediating physical connections with the surrounding environment, the integrin family members are also vital signalling mediators. READ MORE

  4. 7. The Tyrosine Kinase GTK : Signal Transduction and Biological Function

    Author : Cecilia Annerén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. READ MORE

  5. 8. Signal Transduction of Glucagon Secretion

    Author : Elaine Vieira; Erik Gylfe; Lena Eliasson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell biology; secretion; glucagon; store-operated channels; calcium; diabetes; Cellbiologi; Cell biology; Cellbiologi;

    Abstract : Diabetes mellitus is a bihormonal disorder with hyperglycemia due to deficiency of insulin and hypersecretion of glucagon. To improve diabetes treatment it is important to clarify the signal transduction of glucagon secretion. READ MORE

  6. 9. Signal transduction in the brain : modulation of receptor-mediated inositol phospholipid breakdown by potassium and fluoride ions

    Author : Gunnar Tiger; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inositol phospholipid breakdown; muscarinic receptors; potassium; fluoride; rat brain; pig brain;

    Abstract : Neurotransmitter receptor types mediating the generation of intracellular signals are of two types; ligand-gated ion channels and G protein coupled receptors. The effector enzyme phosphoinositide-specific phospholipase C (PLC) is modulated by stimulation of G protein coupled receptors, leading to an increased breakdown of inositol phospholipids ("Ptdlns breakdown"). READ MORE

  7. 10. Mechanisms of integrin signal transduction

    Author : Anne Stefansson; Uppsala universitet; []
    Keywords : ;

    Abstract : .... READ MORE