Search for dissertations about: "Signaling"

Showing result 21 - 25 of 2122 swedish dissertations containing the word Signaling.

  2. 21. Estrogen signaling in stroke : genetic and experimental studies

    Author : Magnus Strand; Tommy Olsson; Jan Hillert; Umeå universitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; intracerebral hemorrhage; ischemic stroke; genetics; ERα; OPG; 17β-estradiol; enriched environment; learning and memory; hippocampus; NGFI-A; Medicine; Medicin;

    Abstract : Stroke is a common and multifactorial disease influenced by genetic and environmental risk factors. It is a highly heterogeneous entity consisting of two main types, ischemic (80%) and hemorrhagic (20%) stroke. The most common form of hemorrhagic stroke is intracerebral hemorrhage (ICH). READ MORE

  4. 22. Neuropeptide signaling in insects : peptide binding sites, tachykinin receptors and SNAP-25

    Author : Helena Anna Dagmar Johard; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Neuropeptide; insects;

    Abstract : .... READ MORE

  5. 23. Calcium and Phospholipases in Orexin Receptor Signaling

    Author : Lisa Johansson; Jyrki Kukkonen; Karl Åkerman; Christopher S. Leonard; Uppsala universitet; []
    Keywords : Physiology; orexin; receptor; calcium; phospholipase; cell signaling; GPCR; Fysiologi;

    Abstract : The neuropeptides orexin-A and -B act as endogenous ligands for G-protein-coupled receptors (GPCRs) called OX1 and OX2 receptors. Previous observations have established that orexin receptors have an ability to couple to different G-proteins and signaling pathways and induce Ca2+ elevations via both receptor-operated Ca2+ channels (ROCs) and store-operated Ca2+ channels (SOCs). READ MORE

  6. 24. Smad signaling in hematopoietic stem cell biology

    Author : Göran Karlsson; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Smad7; Smad4; microarray; retroviral-mediated gene expression; conditional knockout; transforming growth factor beta; smad signaling; hematopoiesis; hematopoietic stem cells; Alk5; Medicine human and vertebrates ; Medicin människa och djur ;

    Abstract : Hematopoietic stem cells (HSCs) are primitive tissue-specific somatic stem cells, responsible for the maintenance and replenishment of the bone marrow (BM) and subsequently the entire blood system. The never-ending ability to differentiate into all the mature hematopoietic lineages makes these HSCs attractive candidates for use in future regenerative medicine. READ MORE

  7. 25. Structural studies of three cell signaling proteins : crystal structures of EphB1, PTPA, and YegS

    Author : Amin Bakali; Pär Nordlund; Wenqing Xu; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein production; structural genomics; cell signaling; Biochemistry; Biokemi;

    Abstract : Kinases and phosphatases are key regulatory proteins in the cell. The disruption of their activities leads ultimately to the abolishment of the homeostasis of the cell, and is frequently correlated with cancer. EphB1 is a member of the largest family of receptor tyrosine kinases. It is associated with neurogenesis, angiogenesis, and cancer. READ MORE