Search for dissertations about: "Simian Immunodeficiency Virus."

Showing result 1 - 5 of 13 swedish dissertations containing the words Simian Immunodeficiency Virus..

  2. 1. Understanding Complex Diseases and Disease Causative Agents : The Machine Learning way

    Author : Zeeshan Khaliq; Jan Komorowski; Steven Bosinger; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pathogens; Influenza A viruses; Human immunodeficiency virus; Simian immunodeficiency virus; Pathogenicity; Cancer; long noncoding RNAs; Machine learning; Host specificity; Host-specific signatures; Bioinformatics; Bioinformatik;

    Abstract : Diseases can be caused by foreign agents – pathogens – such as viruses, bacteria and other parasites, entering the body or by an internal malfunction of the body itself. The partial understanding of diseases like cancer and the ones caused by viruses, like the influenza A viruses (IAVs) and the human immunodeficiency virus, means we still do not have an efficient cure or defence against them. READ MORE

  4. 2. Virus tropism and neutralization response in SIV infection

    Author : Anna Laurén; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Natural science; Medicin människa och djur ; Medicine human and vertebrates ; HIV; SIV; mode of CCR5 use; CD4-independence; macrophage tropism; coreceptor use; neutralization; evolution; pathogenesis;

    Abstract : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. READ MORE

  5. 3. The role of virus neutralization in primate lentivirus pathogenesis

    Author : Yi jun Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The antiviral neutralizing activity of sera from primate lentivirus-infected human and monkey hosts was studied. In addition, factors affecting the neutralization reaction were investigated. In simian immunodeficiency virus (SIVsm)-infected macaque monkeys, SIVsm variants able to escape neutralization emerged regularly. READ MORE

  6. 4. Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection

    Author : Máire Quigley; Karolinska Institutet; Karolinska Institutet; []
    Keywords : CD8 T cells; Human Immunodeficiency Virus-1; Mucosa Associated Lymphoid Tissue; perforin; cytotoxicity; gastrointestinal mucosa; tonsil; CD7 expression; Simian Immunodeficiency Virus.;

    Abstract : The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. READ MORE

  7. 5. Dendritic cell and IgA responses in SIV and HIV-1 pathogenesis

    Author : Johan Söderlund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DC; SIV; HIV-1; macaques; neutralizing antibodies; IgA;

    Abstract : Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV-1) can infect different subsets of dendritic cells (DC). Such cells may therefore not only be involved in the generation of recruitment of naïve T and B lymphocytes in induction of SIV/HIV-1 specific adaptive responses but also transmit virus from port of entrance to the secondary lymphoid compartment generating systemic viral spread. READ MORE