Search for dissertations about: "Skeletal: metabolism"

Showing result 21 - 25 of 168 swedish dissertations containing the words Skeletal: metabolism.

  2. 21. Myosin 1c taking adrenergic metabolism for a spin : More than a motor protein

    Author : Alice Åslund; Tore Bengtsson; Michael Czech; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Glucose transporter; Brown adipose tissue; White adipose tissue; Skeletal muscle; Myosin1c; Nuclear myosin I; Physiology; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Metabolic diseases like type II diabetes (T2D) and obesity largely stems from an unbalanced energy homeostasis with the fails of the insulin pathway to the point in which the glucose homeostasis is severely disturbed leading to hyperglycemia. We have investigated if the β-adrenergic signaling pathways, in both brown adipose tissue (BAT) and skeletal muscle, could be used as a strategy to alleviate metabolic disease. READ MORE

  4. 22. Glucose metabolism in patients with exocrine pancreatic adenocarcinoma

    Author : Johan Permert; Linköpings universitet; []
    Keywords : endocrine pancreatic function; euglycemic hyperinsulinemic clamp; exocrine pancreatic adenocarcinoma; glucose metabolism; glyccogen synthesis; hyperglycemic clamp; immunohistochemistry; insulin resistance; insulin secretion; in situ hybridization; islet amuyloid polypeptide IAPP ; radioimmunoassay; subtotal pancreatectomy; MEDICINE; MEDICIN;

    Abstract : Carc.inoma of the exocrine pancreas is the fifth leading cause of cancer death in the Western world and the survival rate is one of the lowest for cancers of any site. Pancreatic cancer is characterized by pronounced, early cachexia and frequent metabolic complications. READ MORE

  5. 23. Skeletal muscle function and energy metabolism in various nutritional states : a clinical study

    Author : Claes Lennmarken; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The clinical picture of the malnourished patient consists of loss of body fat and lean body mass resulting in weight loss and impaired vital organ function. Weakness and fatigue are often prominent symptoms arising from affected skeletal muscle in these patients. READ MORE

  6. 24. Molecular regulators of glucose and lipid metabolism in skeletal muscle

    Author : Sameer S Kulkarni; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis. Another key feature of a healthy skeletal muscle is its ability to switch between utilization of lipids and glucose as fuel in response to feeding or fasting respectively. READ MORE

  7. 25. Regulation of carbohydrate metabolism in skeletal muscle during and after contraction

    Author : Marie Sandström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Skeletal muscle; glucose transport; contraction; ROS; AMPK; glycogen phosphorylase; glycogen synthase;

    Abstract : It is well known that exercise increases glucose transport into skeletal muscles. The regulation of this transport, however, is poorly understood. READ MORE