Search for dissertations about: "Slemhinnans immunologi"

Showing result 1 - 5 of 9 swedish dissertations containing the words Slemhinnans immunologi.

  1. 1. The role of the epithelial cell in Escherichia coli induced neutrophil migration into the urinary tract

    Author : William Agace; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; E.coli; cytokines; epithelial cell; mucosal inflammation; neutrophil; serology; transplantation; Immunologi; serologi;

    Abstract : This study examined the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. (1) Bacterial induction of neutrophil chemotactic cytokines and their role in neutrophil migration. Uropathogenic E. READ MORE

  2. 2. Regulation of T cell effector functions in the intestinal mucosa

    Author : Petra Holmkvist; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T cells; memory; intestine; cytokines; differentiation; IL-18; inflammation; antigen presentation;

    Abstract : T lymphocytes are a critical cellular component of the adaptive immune response. They are generated in the thymus from bone marrow derived progenitors, where they undergo commitment to the T cell lineage and differentiate and mature into naïve CD4+ and CD8+ T cells. READ MORE

  3. 3. The ontogeny and function of intestinal dendritic cells

    Author : Emma Persson; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenteric lymph nodes; Intestine; Dendritic cells; Gut-homing; Th17 cells; Oral tolerance; Immunity;

    Abstract : The intestinal mucosa presents a huge surface area to the external environment and the intestinal immune system is continually exposed to a wide array of foreign antigens derived from resident intestinal microbiota as well as dietary constituents, including food proteins. In order to maintain intestinal homeostasis, the intestinal immune system relies on the ability to generate tolerogenic responses to innocuous antigen while maintaining the ability to develop effective immune responses to intesinal pathogens. READ MORE

  4. 4. Phenotypic and functional analysis of the mesenchymal stromal cell compartment in the thymus

    Author : Katarzyna Sitnik; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thymus; mesenchymal cells; retinoic acid; thymic epithelial cells;

    Abstract : T cells are key cellular components of the adaptive immune system that play a critical role in our defense against pathogens and cancer but also contribute to pathology in the setting of chronic inflammation and autoimmunity. The thymus constitutes the body's major T cell production site, where bone marrow-derived progenitors migrate in a co-ordinated fashion through anatomically distinct cortical and medullary regions that are composed of epithelial and mesenchymal stromal elements. READ MORE

  5. 5. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling

    Author : Kerstin Wendland; Slemhinnans immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thymus; Thymic epithelial cells; Retinoic acid; T cell development; Stromal Cells;

    Abstract : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. READ MORE