Search for dissertations about: "Sofia Gustafsson"
Showing result 1 - 5 of 6 swedish dissertations containing the words Sofia Gustafsson.
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1. Cannabinoids as modulators of cancer cell viability, neuronal differentiation, and embryonal development
Abstract : Cannabinoids (CBs) are compounds that activate the CB1 and CB2 receptors. CB receptors mediate many different physiological functions, and cannabinoids have been reported to decrease tumor cell viability, proliferation, migration, as well as to modulate metastasis. READ MORE
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2. Translational Aspects of Blood-Brain Barrier Transport and Brain Distribution of Drugs in Health and Disease
Abstract : A high unmet medical need in the area of CNS diseases coincides with high failure rates in CNS drug development. Efficient treatment of CNS disease is constrained by limited entrance of drugs into the brain owing to the blood-brain barrier (BBB), which separates brain from blood. READ MORE
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3. Characterization of HCV Protease Inhibitors : Inhibition and Interaction Studies with Applications for Drug Discovery
Abstract : In this thesis, different approaches based on inhibition and interactions studies, have been used to characterize inhibitors of the non-structural protein 3 (NS3) from the hepatitis C virus (HCV). This involves identification of enzyme inhibitory effects and characterization of interaction mechanisms and kinetics, as well as effects on replication in a cell based system and serum protein binding. READ MORE
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4. Myocardial Tissue Characterization Using Magnetic Resonance Imaging
Abstract : In cardiovascular disease, which is the most common cause of death in the world, early diagnosis is crucial for disease outcome. Diagnosis of cardiovascular disease can be challenging, though. READ MORE
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5. Collaborative development of resource efficient district heating in Sweden
Abstract : An increased recovery of excess heat from industrial processes and thermal power generation could significantly reduce energy demands. Industrial excess heat-based district heating systems are generally considered resource efficient because they reduce the use of fossil fuels and the emissions of greenhouse gases. READ MORE