Search for dissertations about: "Sofia Johansson"

Showing result 1 - 5 of 12 swedish dissertations containing the words Sofia Johansson.

  2. 1. NK cell recognition : adaptability to host factors in normal and diabetic mice

    Author : Sofia Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Natural Killer; NK cell; education; Non obese diabetic; NOD; diabetes; activation; graft; rejection; in vivo; method; receptor; repertoire;

    Abstract : The overall aim of this thesis was to understand the rules, which guide NK cell behavior in vivo. NK cells are part of the innate immune system and are important in defense against certain virus infections and tumorigenic cells. They also play a role in rejecting bone marrow grafts. READ MORE

  4. 2. Post mortem studies on the human alcoholic brain : DNA methylation and molecular responses

    Author : Sofia Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic alcoholism is a multi-factorial psychiatric disease manifested by re-occurring periods of relapse with frequent symptoms of cognitive impairments. There is no explanation to the extreme vulnerability to relapse, since this often occurs without evident molecular or biochemical changes remaining at the time of relapse. READ MORE

  5. 3. The effect of chronic alcoholism on epigenetic patterns regulating gene expression and neurodegeneration in the human brain

    Author : Sofia Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Alcoholism; cognition; drug dependence; brain; frontal cortex; motor cortex; LUMA; epigenetics; methylation; gene expression; endogenous controls; real-time PCR.;

    Abstract : Chronic alcoholism causes about 3.2% of all deaths worldwide. It has an association to about 60 different diseases and injuries with enormous social and economical impact. Despite these facts, very few pharmacological treatments exist and we can still not explain the mechanisms behind addiction, craving and cognitive impairments seen in the abuser. READ MORE

  6. 4. Vertical Nanowire High-Frequency Transistors

    Author : Sofia Johansson; NanoLund: Centre for Nanoscience; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanowires; III-V semiconductors; metal-oxide-semiconductor field-effect transistors; border traps; high-k;

    Abstract : This thesis explores a novel transistor technology based on vertical InAs nanowires, which could be considered both for low-power high-frequency analog applications and for replacing Si CMOS in the continued scaling of digital electronics. The potential of this device - the vertical InAs nanowire MOSFET – lies in the combination of the outstanding transport properties of InAs and the improved electrostatic control of the gate-all-around geometry. READ MORE

  7. 5. Molecular-Level Investigations of Water-Organic Systems of Atmospheric Relevance

    Author : Sofia M. Johansson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; EMB method; desorption kinetics; water uptake; organic surfaces;

    Abstract : It is known that aerosol particles may have warming and/or cooling effects on the climate and negative health effects that depend on their chemical and physical properties. However, current understanding of atmospheric particles’ effects is poor due to the diversity of their constituents and associated variations in properties. READ MORE