Search for dissertations about: "Sofia Svahn Gustafsson"

Found 1 swedish dissertation containing the words Sofia Svahn Gustafsson.

2. 1. Characterization of HCV Protease Inhibitors : Inhibition and Interaction Studies with Applications for Drug Discovery

   Author : Sofia Svahn Gustafsson; U. Helena Danielson; Johan Neyts; Uppsala universitet; []
   Keywords : Biokemi; Biochemistry;

   Abstract : In this thesis, different approaches based on inhibition and interactions studies, have been used to characterize inhibitors of the non-structural protein 3 (NS3) from the hepatitis C virus (HCV). This involves identification of enzyme inhibitory effects and characterization of interaction mechanisms and kinetics, as well as effects on replication in a cell based system and serum protein binding. READ MORE