Search for dissertations about: "Sofia de Mare"

Found 1 swedish dissertation containing the words Sofia de Mare.

2. 1. Regulation of glycerol efflux in adipocytes. Structural and functional studies of the glycerol channel aquaporin 7

   Author : Sofia de Mare; Medicinsk strukturbiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glycerol : metabolism; Lipolysis; X-ray Crystallography; Perilipin 1; Aquaglyceroporin; Aquaporin 7; Adipocytes metabolism; Glycerol : metabolism; adipocyte metabolism; X-ray crystallography; Aquaglyceroporin; Aquaporin 7; Perilipin 1; Lipolysis;

   Abstract : Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffolding for lipolytic proteins on the lipid droplet. READ MORE