Search for dissertations about: "Sofie Haglund"

Found 1 swedish dissertation containing the words Sofie Haglund.

2. 1. Interindividual differences in thiopurine metabolism : studies with focus on inflammatory bowel disease

   Author : Sofie Haglund; Sven Almer; Jan Söderman; Curt Peterson; Åke Nilsson; Linköpings universitet; []
   Keywords : MEDICINE; MEDICIN;

   Abstract : The thiopurines, 6-mercaptopurine and its prodrug azathioprine, are used in the treatment of inflammatory bowel disease, ulcerative colitis and Crohn´s disease. The main active metabolites are the phosphorylated thioguanine nucleotides (6-TGNs) and methylated thioinosine monophosphate (meTIMP). READ MORE